- M.W. Towers, R.L. DeHoog, T.M. Godfrey, L.A. Towers, E.A. Jones, J.B. Ballantyne, J.W. Suliburk, L.S. Eberlin. Development of Low-Flow High-Resolution Desorption Electrospray Ionization Mass Spectrometry Imaging. Journal of the American Society for Mass Spectrometry, 2026, Vol.37 (1), p.152-162.
- E.C. Williams, L. Franz茅n, L. M. Olsson, G. Hamm, S. Oag, M.M. Majumder, J. Denholm, A. Hamidinekoo, M.J. Escudero, M. Vicari, J. Lundeberg, L. Setyo, T.M. Godfrey, L.S. Eberlin, A. Zakirov, J.J. Hornberg, M. Stamou, P.L. St氓hl, A. Ollerstam, J.Y. Tan, I. Mohorianu. Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies. Nature communications, 2026, Vol.17 (1), p.205.
- C.A. Wolfe, S. Povilaitis, M.F. Keating, A.E. Montgomery, B.M. Burt, A.A. Jazaeri, L.S. Eberlin. Next generation MasSpec pen technology: Innovations in instrumentation and medical device development for intraoperative use. International journal of mass spectrometry, 2025, Vol.518, p.117515, Article 117515.
- T.V. Mendes, P.R. Hof, D. Meyer, M. Varghese, L.S. Eberlin. Mass spectrometry imaging of Alzheimer's disease vulnerable and resilient neocortical areas in postmortem formalin鈥恌ixed paraffin鈥恊mbedded and fresh frozen human brains. Alzheimer's & dementia, 2025, Vol.21 (S1), p.n/a.
- K. Sharma, J. Hasen, K. Susztak, L.S. Eberlin, C.R. Anderton, T. Alexandrov, R. Iyengar, 鈥淪patial metabolomics and multiomics integration for breakthroughs in precision medicine for kidney disease鈥, Nature Reviews Nephrology, 2025, DOI 10.1038/s41581-025-01007-3.
- M.W. Towers, R.L. DeHoog, T.M. Godfrey, L.A. Towers, E.A. Jones, J.B. Ballantyne, J.W. Suliburk, L.S. Eberlin. Development of Low-Flow High-Resolution Desorption Electrospray Ionization Mass Spectrometry Imaging. Journal of the American Society for Mass Spectrometry, 2026, Vol.37 (1), p.152-162.
- E.C. Williams, L. Franz茅n, L. M. Olsson, G. Hamm, S. Oag, M.M. Majumder, J. Denholm, A. Hamidinekoo, M.J. Escudero, M. Vicari, J. Lundeberg, L. Setyo, T.M. Godfrey, L.S. Eberlin, A. Zakirov, J.J. Hornberg, M. Stamou, P.L. St氓hl, A. Ollerstam, J.Y. Tan, I. Mohorianu. Spatially resolved integrative analysis of transcriptomic and metabolomic changes in tissue injury studies. Nature communications, 2026, Vol.17 (1), p.205.
- C.A. Wolfe, S. Povilaitis, M.F. Keating, A.E. Montgomery, B.M. Burt, A.A. Jazaeri, L.S. Eberlin. Next generation MasSpec pen technology: Innovations in instrumentation and medical device development for intraoperative use. International journal of mass spectrometry, 2025, Vol.518, p.117515, Article 117515.
- T.V. Mendes, P.R. Hof, D. Meyer, M. Varghese, L.S. Eberlin. Mass spectrometry imaging of Alzheimer's disease vulnerable and resilient neocortical areas in postmortem formalin鈥恌ixed paraffin鈥恊mbedded and fresh frozen human brains. Alzheimer's & dementia, 2025, Vol.21 (S1), p.n/a.
- K. Sharma, J. Hasen, K. Susztak, L.S. Eberlin, C.R. Anderton, T. Alexandrov, R. Iyengar, 鈥淪patial metabolomics and multiomics integration for breakthroughs in precision medicine for kidney disease鈥, Nature Reviews Nephrology, 2025, DOI 10.1038/s41581-025-01007-3.
- R. Dehoog , A. Al-Fartosi , M.N.C. Lin, N. Zarrin-Khameh, R.R. Huang, L.S. Eberlin, J. Suliburk, 鈥淎nalytical Validation of Desorption Electrospray Ionization Mass Spectrometry Imaging for Classification of Thyroid Fine Needle Aspiration Biopsies鈥, Clinical Chemistry, 2025, DOI 10.1093/clinchem/hvaf086.722.
- T. Godfrey, B. Acidi, P. Fernandes, S. Bench, A.Gonz谩lez, W.D. Yu, Y.H. Wang, H.T. Cao, L.S. Eberlin, 鈥淓x-Vivo Evaluation of the MasSpec Pen Technology for Hepatocellular Carcinoma Margin Assessment鈥, Clinical Chemistry, 2025, DOI 10.1093/clinchem/hvaf086.729.
- C.A. Wolfe, S. Povilaitis, M.F. Keating , A.E. Montgomery, B.M. Burt, A.A. Jazaeri, L.S. Eberlin, 鈥淣ext generation MasSpec pen technology: Innovations in instrumentation and medical device development for intraoperative use鈥, International Journal of Mass Spectrometry, 2025, DOI 10.1016/j.ijms.2025.117515.
- A. Salama, O.H. Ou, M. Dwenger , C. Wells, A. Gebreil, J. Miller, K. Abou FarraJ, Y.B. Nong, R. WahiD , H. Abdelhafez, M. Arai, M. Hamouda, P.R. Mathew, W. Elhelaly, J. Huelsmann, S. Bench, S.W. Kang, V. Rodriguez, D. Kraushaar, H.S. Lee, L.S. Eberlin, B. Hill, T. Rosengart, R. Abouleisa, T. Mohamed , 鈥淪pontaneously proliferating cardiomyocytes are sensitized to proliferate through retinoic acid dependent signaling鈥, Circulation Research, 2025, DOI 10.1161/res.137.suppl_1.Thu024.
- C.C. Lin, T.L. Pulliam, J.J. Han, J.Q. Xu, C.V. ReciO, S.R.. Wilkenfeld, Y. Shi, M. Kushwaha, S. Bench, E. Ruiz, S. Senthilkumar, J. Dileep , P.D.A. Shepherd, N.M. Navone, A.R. Klekers, E.M. Whitley, M.M. Ittmann , L.S. Eberlin, W.Y. Wang, D.E. Frigo, 鈥淐holesterol metabolism regulated by CAMKK2-CREB signaling promotes castration-resistant prostate cancer鈥, Cell Reports, 2025, DOI 10.1016/j.celrep.2025.115792.
- M. Lin, E.H. Seeley, S. Ledet , C. Salazar , M.T. Breen, L.S. Eberlin, 鈥淢ass spectrometry imaging reveals alterations in protein and N-glycan molecular signatures in endometriosis tissues鈥, Analytical and Bioanalytical Chemistry, 2025, DOI 10.1007/s00216-025-05930-z.
- A. Reis, C.P. Carvalho, I.L. de Lima, F.R.P. Mansoldo, A.B. Vermelho, R.C. Simas, L.S. Eberlin, M.N. Eberlin, 鈥"Touch&Play" Wood Typification by the MasSpec Pen鈥, Journal of Mass Spectrometry, 2025, DOI10.1002/jms.5133.
- A.N. Gatmaitan, K. Weaver , S.P. Badal, H.E. Bird, A. Huhn, C. Hussey, W.A. Clarke, L.S. Eberlin, 鈥淒evelopment and Application of the Modular MasSpec Pen System for Clinical Opioid Screening鈥, Analytical Chemistry, 2025, DOI10.1021/acs.analchem.5c00558.
- T.M. Godfrey, Y. Shanneik,W.Q. Zhang,T. Tran, N. Verbeeck, N.H. Patterson, F.E. Jackobs, C. Nagi, M. Ramineni, L.S. Eberlin, 鈥淚ntegrating Ambient Ionization Mass Spectrometry Imaging and Spatial Transcriptomics on the Same Cancer Tissues to Identify RNA-Metabolite Correlations鈥, Angewandte Chemie-International Edition, 2025, DOI10.1002/anie.202502028.
- T.M. Godfrey, Y. Shanneik, W.Q. Zhang, T. Tran, N. Verbeeck, N.H. Patterson, F.E. Jackobs, M. Ramineni, C. Nagi, L.S. Eberlin, 鈥淚ntegrating spatial metabolomics and spatial transcriptomics on the same cancer tissue sections to detect gene-metabolite correlations鈥, Cancer Research, 2025, DOI10.1158/1538-7445.AM2025-150.
- Y. Shanneik, B. Burt, M. Ramineni, L.S. Eberlin, 鈥淎dvancing non small cell lung cancer detection and subtyping by MasSpec Pen technology鈥, Cancer Research, 2025, DOI10.1158/1538-7445.AM2025-4584.
- L.Q. Yu, K. Liebenberg, Y.C. Shen, F.S. Liu, Z. Xu, X.X. Hao, L. Wu, W.J. Zhang, h.l. Chan, b. Wei, P.L. Lorenzi, Y. Gao, I. Bado , L. Becerra-Dominguez, C.H. Rivas, S. Aguirre, B.C. Pingel , Y.H. Wu, Y.F. Ding, J. Liu, D.G. Edwards, L.S. Eberlin, X.H.F. Zhang, 鈥淭umor-derived arachidonic acid reprograms neutrophils to promote immune suppression and therapy resistance in triple-negative breast cancer鈥, Immunity, 2025, DOI10.1016/j.immuni.2025.03.002.
- J.R. Shuluk , C.D. Wight, J.R. Howard, M.E. King, S.R. Moor, R.J. Dehoog, S.D. Dahlhauser, L.S. Eberlin, E.V. Anslyn, 鈥淎 Workflow Enabling the Automated Synthesis, Chain-End Degradation, and Rapid Mass Spectrometry Analysis for Molecular Information Storage in Sequence-Defined Oligourethanes鈥, JACS AU, 2025, DOI10.1021/jacsau.4c01070.
- A.L. Seidinger, F.L.T. Silva, M.F. Euz茅bio, A.C. Krieger, J. Meidanis, J.M. Gutierrez, T.M.S. Bezerra, L. Queiroz, A.A.R. Silva, I.L. Hoffmann, C.M.M. Daiggi, H. Tedeschi, M.N. Eberlin, L.S. Eberlin, J.A. Yunes, A.M. Porcari, I.A. Cardinalli , 鈥淭umor-Promoted Changes in Pediatric Brain Histology Can Be Distinguished from Normal Parenchyma by Desorption Electrospray Ionization Mass Spectrometry Imaging鈥, Biomedicines, 2025, DOI10.3390/biomedicines12112593.
- K.R.K. Reddy,D.W.B. Piyarathna,, J.H. Park, V. Putluri, A.M. Kamal, J. Xu, D. Kraushaar, S.X. Huang,S.Y. Jung , L.S. Eberlin, , Kittles, RA, Parsawar, K, Siddiqui, MM, Gao, JJ, Gramer, AL, Bollag, RJ, Terris, MK , Lotan, Y, Creighton, CJ , Lerner, SP, Sreekumar, A, Kaipparettu, BA, Putluri, N, 鈥淢itochondrial reprogramming by activating OXPHOS via glutamine metabolism in African American patients with bladder cancer鈥, JCI INSIGHT, 2024, DOI10.1172/jci.insight.172336.
- N.D. Fleming, C.A. Wolfe, M. Keating, M. Sans, K.M. Rangel, C. Sunny, S.N. Westin, A.A. Jazaeri, P.T. Soliman, J.S. Taylor, R.T. Hillman, J.A. How, B. Lawson,A.K. Sood, L.S. Eberlin, 鈥淔easibility of using the handheld MasSpec pen technology for intraoperative identification of ovarian cancer during tumor reductive surgery鈥, Journal of Clinical Oncology, 2024, Volume:4, Issue:16, Supplement:S, Meeting Abstract:5573.
- M.F Keating, C.A. Wolfe, K. Liebenberg, A. Montgomery, A.M. Porcari, N.D.A. Fleming, A. Makarov, L. S. Eberlin 鈥淒ata Acquisition and Intraoperative Tissue Analysis on a Mobile, Battery-Operated Orbitrap Mass Spectrometer鈥, Analytical Chemistry, 2024, in press
- C.L. Feider, A.V. Bensussan, M.F. Keating, J.Q. Lin, M.W. Sun, R.Tibshirani, C. Pirko, K.A. Brahmbhatt, A.R. Al-Fartosi, A.M. Thompson, E. Bonefas, J. Suliburk, S.A. Carter, L.S. Eberlin, 鈥淚ntraoperative Evaluation of Breast Tissues During Breast Cancer Operations Using the MasSpec Pen鈥, JAMA Network Open, 2024, 7(3), e242684.
- D. Awad, P.H.A. Cao, T.L. Pulliam, M.L. Spradlin, E. Subramani, T.V. Tellman, C.F. Ribeiro, R. Muzzioli, B.E. Jewell, H. Pakula, J.J. Ackroyd, M.M. Murray, J.J. Han, M. Leng, A. Jain, B. Piyarathna, J. Liu, X. Song, J. Zhang, A.R. Klekers, J.M. Drake, M.M. Ittmann, C. Coarfa, D. Piwnica-Worms, M.C. Farach-Carson, M. Loda, L.S. Eberlin, D.E. Frigo, 鈥淎dipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity鈥, Cancer Research, 2024, 84 (5), 703-724.
- S. Corvigno, S. Badal, M.L Spradlin, M. Keating, I. Pereira, E. Stur, Emine Bayraktar, K.I. Foster, N.W. Bateman, W. Barakat, K.M. Karcy, T.P. Conrads, G.L. Maxwell, P.L. lorenzi, S.K. Lutgendorf, Y. Wen, L. Zhao, P.H. Thaker, M.J. Goodheart, J. Liu, N. Fleming, S. Lee, L.S. Eberlin, A.K. Sood. 鈥淚n situ profiling reveals metabolic alterations in the tumor microenvironment of ovarian cancer after chemotherapy鈥, npj Precis. Onc., 2023, 7, 115.
- J.R. Chappel, M.E. King, J. Fleming, L.S. Eberlin*, D.M. Reif*, E.S. Baker*, 鈥淎ggregated Molecular Phenotype Scores: Enhancing Assessment and Visualization of Mass Spectrometry Imaging Data for Tissue-Based Diagnostics鈥, Analytical Chemistry, 2023, 95, 34, 12913鈥12922.
- R.J. DeHoog, M.E. King, M.F. Keating, J. Zhang, M. Sans, C.L. Feider, K.Y. Garza, A. Bensussan, A. Krieger, J.Q. Lin, S. Badal, E. Alore, C. Pirko, K. Brahmbhatt, W. Yu, R. Grogan, L.S. Eberlin*, and J. Suliburk*, 鈥淚ntraoperative Identification of Thyroid and Parathyroid Tissues during Human Cervical Endocrine Surgery using the MasSpec Pen鈥, JAMA Surgery, 2023, 158 (10), 1050-1059.
*co-corresponding authors - D. Unsihuay, W.S. Phipps, A.G. Paulovich, J.R. Chapman, A. Ducret, L.S. Eberlin, J.M. Spraggins, R.J.A Goodwin. 鈥淭issue Mass Spectrometry: How Solid Is Our Future?鈥, Clinical Chemistry, 2023, 69(7):676-683.
- R.J. DeHoog, M. Lin, G. Roman, R. Martin, J. Suliburk, and L.S. Eberlin, 鈥淓valuating the Generalizability of Predictive Classifiers Built from DESI Imaging Lipid Data across Mass Spectrometry Platforms鈥, Journal of the American Society for Mass Spectrometry, 2023, 34, 7, 1532-1537.
36. L.S. Eberlin, 鈥淒isease Detection and Diagnostics: Multidisciplinary Approaches to Address Medical challenges鈥, JACS Au, 2023, 3, 5, 1264鈥1266. - A.C. Krieger, L.A. Macias, J.C. Goodman, J.S. Brodbelt, and L.S. Eberlin, 鈥淢ass Spectrometry Imaging Reveals Abnormalities in Cardiolipin Composition and Distribution in Astrocytoma Tumor Tissues鈥, Cancers, 2023, 15, 2842.
- M.E. King, R. Yuan, J. Chen. K. Pradhan, I. Sariol, S. Li, A. Chakraborty, O. Ekpenyong, J.H. Yearley, J.C. Wong, L. Z煤帽iga, D. Tomazela, M. Beaumont*, J.H. Han*, and L.S. Eberlin*, 鈥淟ong-chain polyunsaturated lipids associated with responsiveness to anti-PD-1 therapy are colocalized with immune infiltrates in the tumor microenvironment鈥, Journal of Biological Chemistry, 2023, 299, 3, 102902.
*co-corresponding authors - M.E. King, M. Lin, M. Spradlin, and L.S. Eberlin, 鈥淎dvances and Emerging Medical Applications of Direct Mass Spectrometry Technologies for Tissue Analysis鈥, Annual Reviews in Analytical Chemistry, 2023, 16, 1-25.
- D. Glassman, M.S. Kim, M. Spradlin, S. Badal, M. Taki, P. Bhattacharya, P. Dutta, C.V. Kingsley, K.I. Foster, O. Animasahun, J.H. Jeon, A. Achreja, A. Jayaraman, P. Kumar, M. Nenwani, F. Wuchu. E. Bayraktar, Y. Wu, E. Stur, L. Mangala, S. Lee, T.A. Yap, S.N. Westin, L.S. Eberlin, D. Nagrath, A.K. Sood, 鈥淓xploiting metabolic vulnerabilities after anti-VEGF antibody therapy in ovarian cancer鈥, iScience, 2023, 106020.
- A.V. Moura, D.C. de Oliveira, A.A.R. Silva, J.R. da Rosa, P.H.D. Garcia, P.H.G. Sanches, K.Y. Garza, F.M.M. Mendes, M. Lambert, J.M. Gutierrez, N.M. Granado, A.C dos Santos, I.L. de Lima, L.D. de Oliveira Negrini, M.A. Antonio, M.N. Eberlin, L.S. Eberlin, A.M. Porcari, 鈥淯rine Metabolites Enable Fast Detection of COVID-19 Using Mass Spectrometry鈥, Metabolites, 2022, 12(11):1056.
- S.C. Povilaitis, A. Chakraborty, L.M. Kirkpatrick, R.D. Downey, S.B. Hauger, L.S. Eberlin, 鈥淚dentifying Clinically Relevant Bacteria Directly from Culture and Clinical Samples with a Handheld Mass Spectrometry Probe鈥, Clinical Chemistry, 2022, 68, 11, 1459-1470.
- K.F. Handley, T.T. Sims, N.W. Bateman, D. Glassman, K.I. Foster, S. Lee, J. Yao, H. Yao, B.M. Fellman, J. Liu, Z. Lu, K.A. Conrads, B.L. Hood, W. Barakat, L. Zhao, J. Zhang, S.N. Westin, MD, J. Celestino, K.M. Rangel, S. Badal, I. Pereira, P.T. Ram, G. L. Maxwell, L.S. Eberlin, A. Futreal, R.C. Bast, N.D. Fleming, T.P. Conrads, A.K. Sood 鈥淐lassification of High-Grade Serous Ovarian Cancer Using Tumor Morphologic Characteristics鈥, JAMA network Open, 2022, 5, p.e2236626.
- M. Lin, M.S. Blevins, M. Sans, J.S. Brodbelt, L.S. Eberlin, 鈥淒eeper Understanding of Solvent-Based Ambient Ionization Mass Spectrometry: Are Molecular Profiles Primarily Dictated by Extraction Mechanisms?鈥, Analytical Chemistry, 2022, 94, 42, 14734-14744.
- A.C. Krieger, S.C. Povilaitis, P. Gowda, L.A. O鈥機onnell, L.S.Eberlin, 鈥淣oninvasive Detection of Chemical Defenses in Poison Frogs Using the MasSpec Pen鈥, American Chemical Society, 2022, 2, 5, 475-484.
- M. Lin, L.S. Eberlin, E. Seeley, 鈥淩educed Hemoglobin Signal and Improved Detection of Endogenous Proteins in Blood-Rich Tissues for MALDI Mass Spectrometry Imaging鈥, Journal of the American Society for Mass Spectrometry, 2022, 33, 296鈥303.
- L. Macias, K.Y. Garza, C.L. Feider, L.S. Eberlin, J.S. Brodbelt, 鈥淩elative Quantitation of Unsaturated Phosphatidylcholines using 193 nm Ultraviolet Photodissociation Parallel Reaction Monitoring Mass Spectrometry鈥, Journal of the American Chemical Society, 2021, 143, 14622鈥14634.
- K. Y. Garza, A. A. Silva, J. R. Rosa, M. F. Keating, S. C. Povilaitis, M. Spradlin, P. H. Sanches, A. Varao Moura, J. Marrero Gutierrez, J. Q. Lin, J. Zhang, R. J. DeHoog, A. Bensussan, S. Badal, D. Cardoso de Oliveira, P. H. Dias Garcia, L. Dias de Oliveira Negrini, M. Antonio, T. C. Canevari, M. N. Eberlin, R. Tibshirani, L. S. Eberlin*, and A. M. Porcari*, 鈥淩apid screening of COVID-19 directly from Clinical Nasopharyngeal Swabs using The MasSpec Pen,鈥 Analytical Chemistry, 2021, 93, 12582鈥12593.
*co-corresponding authors - M. E. King, J. Zhang, J.Q. Lin, K.Y. Garza, R.J. DeHoog, C.L. Feider, A. Bensussan, M. Sans, A. Krieger, S. Badal, M.F. Keating, S. Woody, S. Dhingra, W. Yu, C. Pirko, K. Brahmbhatt, G.Van Buren, W.E. Fisher, J. Suliburk, and L.S. Eberlin, 鈥淩apid Diagnosis and Tumor Margin Assessment During Pancreatic Cancer Surgery with the MasSpec Pen Technology鈥, Proceedings of the National Academy of Sciences U.S.A., 2021, 118, e2104411118.
- J. Zhang, M. Sans, R.J. DeHoog, K.Y. Garza, M.E. King, C.L. Feider, A. Bensussan, M.F. Keating, J.Q. Lin, S. Povilaitis, N. Katta, T.E. Milner, W. Yu, C. Nagi, S. Dhingra, C. Pirko, K.A. Brahmbhatt, G. Van Buren, S. Carter, A. Thompson, R.H. Grogan, J. Suliburk, and L.S. Eberlin, 鈥淐linical Translation and Evaluation of the MasSpec Pen Technology for Surgical Use鈥, Clinical Chemistry, 2021, 67, 1271鈥1280.
- C.L. Feider, A. Gatmaitan, T. Hooper, A. Chakraborty, P. Gowda, E. Buchanan, and L.S. Eberlin, 鈥淚ntegrating the MasSpec Pen with Sub-Atmospheric Pressure Chemical Ionization for Rapid Chemical Analysis and Forensic Applications鈥, Analytical Chemistry, 2021, 93, 21, 7549鈥7556.
- A. Vaughn, R.J. DeHoog, L.S. Eberlin, and D. R. Appling, 鈥淢etabotype analysis of Mthfd1l-null mouse embryos using desorption electrospray ionization imaging mass spectrometry鈥, Analytical and Bioanalytical Chemistry, 2021, 413, 3573鈥3582.
- A. N. Gatmaitan, J. Q. Lin, J. Zhang, and L. S. Eberlin, 鈥淩apid Analysis and Authentication of Meat Using the MasSpec Pen Technology,鈥 Journal of Agricultural and Food Chemistry, 2021, 69, 11, 3527鈥3536.
- A. V. Bensussan, J. Lin, C. Guo, R. Katz, S. Krishnamurthy, E. Cressman, and L. S. Eberlin, 鈥淒istinguishing Non-Small Cell Lung Cancer Subtypes in Fine Needle Aspiration Biopsies by Desorption Electrospray Ionization Mass Spectrometry Imaging,鈥 Clinical Chemistry, 2020, 66, 1424-1433. 鈥爁eatured on cover
- J. Zhang, M. Sans, K. Y. Garza, and L. S. Eberlin, 鈥淢ass Spectrometry Technologies to Advance Care for Cancer Patients in Clinical and Intraoperative Use,鈥 Mass Spectrometry Reviews, 2020, DOI: 10.1002/mas.21664.
- G. Zhang, J. Zhang, R.J. DeHoog, S. Pennathur, C.R. Anderton, M.A. Venkatachalam, T. Alexandrov, L.S. Eberlin, and K. Sharma, 鈥淒ESI MSI and METASPACE indicates lipid abnormalities and altered mitochondrial membrane components in diabetic renal proximal tubules鈥, Metabolomics, 2020, 16, 11.
- M. F. Keating, J. Zhang, C. L. Feider, S. Retailleau, R. Reid, A. Antaris, B. Hart, G. Tan, T. E. Milner, K. Miller, and L. S. Eberlin, 鈥淚ntegrating the MasSpec Pen to the da Vinci Surgical System for In Vivo Tissue Analysis during a Robotic Assisted Porcine Surgery,鈥 Analytical Chemistry, 2020, 92, 11535-11542.
- C.L. Feider, L.A. Macias, J. Brodbelt, and L.S. Eberlin, 鈥淒ouble Bond Characterization of Free Fatty Acids Directly from Biological Tissues by Ultraviolet Photodissociation鈥, Analytical Chemistry, 2020, 92, 8396-8395.
- M. Sans, A. Krieger, B.R. Wygant, K.Y. Garza, B.C. Mullins, and L.S. Eberlin, 鈥淪patially Controlled Molecular Analysis of Biological Samples Using Nanodroplet Arrays and Direct Droplet Aspiration,鈥 Journal of the American Society for Mass Spectromtry. 2020, 31, 418-428.
- J. Zhang, S. Q. Li, J. Q. Lin, W. Yu, and L. S. Eberlin, 鈥淢ass Spectrometry Imaging enables Discrimination of Renal Oncocytoma from Renal Cell Cancer Subtypes and Normal Kidney Tissues,鈥 Cancer Research, 2020, 80, 689-698.
- L.A. Macias, C.L. Feider, L.S. Eberlin, and J.S. Brodbelt, 鈥淗ybrid 193 nm Ultraviolet Photodissociation Mass Spectrometry Localizes Cardiolipin Unsaturations,鈥 Analytical Chemistry, 2019, 91, 12509-12516
- R. DeHoog, J. Zhang, E. Alore, J.Q. Lin, W. Yu, S. Woody, C. Almendariz, M. Lin, A.F. Engelsman, S.B. Sidhu, R. Tibshirani, J. Suliburk, and L.S. Eberlin, 鈥淧reoperative Metabolic Classification of Thyroid Nodules using Mass Spectrometry Imaging of Fine Needle Aspiration Biopsies,鈥 Proceedings of the National Academy of Sciences U.S.A. 2019, 116, 21401-21408.
- C.L. Feider, S. Woody, S. Ledet, J. Zhang, K. Sebastian, M.T. Breen, and L.S. Eberlin, 鈥淢olecular Imaging of Endometriosis Tissues using Desorption Electrospray Ionization Mass Spectrometry,鈥 Scientific Reports. 2019, 9, 15690.
- C.L. Feider, A. Krieger, R.J. DeHoog, and L.S. Eberlin, 鈥淎mbient Ionization Mass Spectrometry: Recent Developments and Applications,鈥 Analytical Chemistry, 2019, 91, 4266-4290
- M. Sans, J. Zhang, J.Q. Lin, C.L. Feider, N. Giese, M.T. Breen, K. Sebastian, J. Liu, A.K. Sood, and L.S. Eberlin, 鈥淧erformance of the MasSpec Pen for Rapid Diagnosis of Ovarian Cancer,鈥 Clinical Chemistry 2019, 65, 674-683. *featured on cover
- C.L. Feider, R.J. DeHoog, M. Sans, J. Zhang, A. Krieger, and L.S. Eberlin, 鈥淒ESI Spray Stability in the Negative Ion Mode Is Dependent on Relative Humidity,鈥 Journal of the American Society for Mass Spectrometry, 2019, 30, 376-380.
- O. Simoska, M. Sans, M.D. Fitzpatrick, C.M. Crittenden, L.S. Eberlin, J.B. Shear, and K.J. Stevenson, 鈥淩eal-Time Electrochemical Detection of Pseudomonas aeruginosa Phenazine Metabolites Using Transparent Carbon Ultramicroelectrode Arrays,鈥 ACS Sensors, 2019, 4, 170-179.
- A.M. Porcari, J. Zhang, K.Y. Garza, R.M. Rodrigues-Peres, J. Lin, J.H. Young, R. Tibshirani, C. Nagi, G.R. Paiva, S.A. Carter, L.O. Sarian, M.N. Eberlin, and L.S. Eberlin, 鈥淎 Multi-Center Study Using Desorption Electrospray Ionization Mass Spectrometry Imaging for Breast Cancer Diagnosis鈥 Analytical Chemistry, 2018, 90, 11324鈥11332.
- D.R. Klein, C.L. Feider, K.Y. Garza, J.Q. Lin, L.S. Eberlin, and J.S. Brodbelt, 鈥淒esorption Electrospray Ionization Coupled with Ultraviolet Photodissociation for Characterization of Phospholipid Isomers in Tissue Sections,鈥 Analytical Chemistry, 2018, 90, 10100-10104.
- K.Y. Garza, C. Feider, D.R. Klein, J. Rosenberg, J.S. Brodbelt, and L.S. Eberlin, 鈥淒esorption Electrospray Ionization Mass Spectrometry Imaging of Proteins Directly from Biological Tissue Sections,鈥 Analytical Chemistry 2018, 90, 7785-7789.
- Gharpure, S. Pradeep, M. Sans, R. Rupaimoole, C. Ivan, S.Y. Wu, A.S. Nagaraja, L.S. Mangala, X. Zhang, M. Haemmerle, W. Hu, C. Rodriguez-Aguayo, M. McGuire, G.A. Pena, R. Kondetimmanahalli, R. Nini, P. Koppula, P. Ram, S.L. Tucker, G. Lopez-Berestein, K. Baggerly, L.S. Eberlin, and A.K. Sood, 鈥淔ABP4 as a molecular determinant of residual disease in ovarian cancer鈥, Nature Communications, 2018, 9:2923.
- M. Sans, C.L. Feider, and Livia S. Eberlin, 鈥淎dvances in Mass Spectrometry Imaging coupled to Ion Mobility Spectrometry for Enhanced Imaging of Biological Tissues鈥, Current Opinion in Chemical Biology, 2017, 42, 138-146.
- J. Zhang, J. Rector, J. Lin, J.H. Young, M. Sans, N. Katta, N. Giese, W. Yu, C. Nagi, J. Suliburk, J. Liu, A. Bensussan, R.J. DeHoog, K.Y. Garza, B. Ludolph, A.G.Sorace, A. Syed, A. Zahedivash, T. Milner, and L.S. Eberlin, 鈥淣ondestructive Tissue Analysis for Ex Vivo and In Vivo Cancer Diagnosis using a Handheld Mass Spectrometry System鈥, Science Translational Medicine, 2017, 9, eaan3968. 鈥爁eatured in the cover; Altmetric Score: 1679
76. - M. Sans, K. Gharpure, R. Tibshirani, J. Zhang, L. Liang, J. Liu, A.K. Sood, and L. S. Eberlin, 鈥淢etabolic Markers and Statistical Prediction of Serous Ovarian Cancer Aggressiveness by Ambient Ionization Mass Spectrometry Imaging鈥, Cancer Research, 2017, 77, 2903-2913.
- J. Zhang, C. Feider, C. Nagi, W. Yu, S. A. Carter, J. Suliburk, H. S. Tran Cao, and L. S. Eberlin, 鈥淒etection of Metastatic Breast and Thyroid Cancer in Lymph Nodes by Desorption Electrospray Ionization Mass Spectrometry Imaging鈥, Journal of the American Society of Mass Spectrometry, 2017, 28, 1166-1174.
- C.L. Feider, N. Elizondo, and L.S. Eberlin, 鈥淎mbient Ionization and FAIMS Mass Spectrometry for Enhanced Imaging of Multiply Charged Molecular Ions in Biological Tissues鈥, Analytical Chemistry, 2016, 88, 11533-11541.
- J. Zhang, W. Yu, S. Ryu, J. Lin, G. Buentello, R. Tibshirani, J. Suliburk, and L.S. Eberlin, 鈥淐ardiolipins are biomarkers of mitochondria-rich thyroid oncocytic tumors鈥, Cancer Research, 2016, 76, 6588-6597.
- J. Zhang, W. Yu, J. Suliburk, and L.S. Eberlin, 鈥淲ill ambient ionization mass spectrometry become an integral technology in the operating room of the future?鈥, Clinical Chemistry, 2016, 62, 1172-1174.
- D.R. Ifa and L.S. Eberlin, 鈥淎mbient Ionization Mass Spectrometry for Cancer Diagnosis and Surgical Margin Evaluation鈥, Clinical Chemistry, 2016, 62, 111-123.
- A.M. Gouw, L.S. Eberlin, K. Margulis, D.K. Sullivan, G.G. Toal, L. Tong, R.N. Zare, D.W. Felsher, 鈥淥ncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma鈥, Proceedings of the National Academy of Sciences U.S.A., 2017, 114, 4300-4305.
- L.S. Eberlin, K. Margulis, I. Planell-Mendez, R.N. Zare, R. Tibshirani, T.A. Longacre, M. Jalali, J.A. Norton, and G.A. Poultsides, 鈥淧ancreatic Cancer Surgical Resection Margins: Molecular Assessment by Mass Spectrometry Imaging鈥, Plos Medicine, 2016, 13, e1002108.
- M.T. Dulay, L.S. Eberlin, and R.N. Zare, 鈥淧rotein Analysis by Ambient Ionization Mass Spectrometry Using Trypsin-Immobilized Organosiloxane Polymer Surfaces鈥, Analytical Chemistry, 2015, 87, 12324-12330.
- E.H. Shroff, L.S. Eberlin, V.M. Dang, A.M. Guow, M. Gabay, S.J. Adam, D.I. Bellovin, P.T. Tran, W.M. Philbrick, A. Garcia-Ocana, S.C. Casey, Y.L. Li, C.V. Dang, R.N. Zare and D.W. Felsher, 鈥淢YC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism鈥, Proceedings of the National Academy of Sciences U.S.A., 2015, 112, 6539-6544.
- K.D. Bemis, A. Harry, L.S. Eberlin, C. Ferreira, S.M. van de Ven, P. Mallick, M. Stolowitz, O. Vitek, 鈥淐ardinal: an R package for statistical analysis of mass spectrometry-based imaging experiments鈥, Bioinformatics, 2015, 31, 2418-2420.
- E.H. Shroff, L.S. Eberlin, V.M. Dang, A.M. Guow, M. Gabay, S.J. Adam, D.I. Bellovin, P.T. Tran, W.M. Philbrick, A. Garcia-Ocana, S.C. Casey, Y.L. Li, C.V. Dang, R.N. Zare and D.W. Felsher, 鈥淢YC oncogene overexpression drives renal cell carcinoma in a mouse model through glutamine metabolism鈥, Proceedings of the National Academy of Sciences of the U.S.A., 2015, 112, 6539-6544.
- L.S. Eberlin, M. Gabay, A.C. Fan, R. Tibshirani, D. Felsher, and R.N. Zare, 鈥淎lteration of the Lipid Profile in Lymphomas Induced by MYC Overexpression鈥, Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111, 10450-10455.
- L.S. Eberlin, J.V. Mulcahy, A. Tzabazis, J. Zhang, M. Logan, H.J. Roberts, G.K. Lee, D.C. Yeomans, J. Du Bois, and R.N. Zare, 鈥淰isualizing Dermal Permeation of Sodium Channel Modulators by Mass Spectrometric Imaging鈥, Journal of the American Chemical Society, 2014, 136, 6401-6405.
- L.S. Eberlin, R. Tibshirani, J. Zhang, T.A. Longacre, G. Berry, D.B. Bingham, J.A. Norton, R.N. Zare and G.A. Poultsides, 鈥淢olecular Assessment of Gastric Cancer Surgical Resection Margins by Mass Spectrometric Imaging鈥, Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111, 2436-2441.
- S. Santagata*, L.S. Eberlin*, I. Norton, D. Calligaris, D.R. Feldman, J.L. Ide, X. Liu, J.S. Wiley, M.L. Vestal, S.H. Ramkissoon, D.A. Orringer, K.K. Gill, I.F. Dunn, D. Dias-Santagata, K.L. Ligon, F.A. Jolesz, A.J. Golby, R.G. Cooks, and N.Y.R. Agar, 鈥淚ntraoperative mass spectrometry mapping of an onco-metabolite to guide brain tumor surgery鈥, Proceedings of the National Academy of Sciences of the U.S.A., 2014, 111, 11121-11126. [*equal contribution]
- D. Calligaris, I. Norton, D.R. Feldman, J.L. Ide, I.F. Dunn, L.S. Eberlin, R.G. Cooks, F.A. Jolesz, A.J. Golby, S. Santagata and N.Y.R. Agar, 鈥 Mass spectrometry imaging as a tool for surgical decision-making鈥, Journal of Mass Spectrometry, 2013, 48, 1178-1187.
- L.S. Eberlin, I. Norton, D. Orringer, I. F. Dunn, X. Liu, J.L. Ide, A.K. Jarmusch, K.L. Ligon, F.A. Jolesz, A.J. Golby, S. Santagata, N.Y. R. Agar and R.G. Cooks, 鈥淎mbient Mass Spectrometry for the Intraoperative Molecular Diagnosis of Human Brain Tumors鈥, Proceedings of the National Academy of Sciences of the U. S.A., 2013, 110, 1611-1616.
- B. Gholami, I. Norton, L.S. Eberlin, N.Y.R. Agar, 鈥淎 Statistical Modeling Approach for Tumor-Type Identification in Surgical Neuropathology Using Tissue Mass Spectrometry Imaging鈥, IEEE Journal of Biomedical and Health Informatics, 2013, 17, 734-744
- C. Wu, A.L. Dill, L.S. Eberlin, R.G. Cooks and Demian R. Ifa, 鈥淢ass Spectrometry Imaging under Ambient Conditions鈥, Mass Spectrometry Reviews, 2013, 32, 218-243.
- A.H.L. Machado, H.M.S. Milagre, L.S. Eberlin, A.A. Sabino, C.R.D. Correia, M.N. Eberlin, 鈥淒ba-free palladium intermediates of the Heck-Matsuda reaction鈥, Organic & Biomolecular Chemistry, 2013, 11, 3277-3281.
- A.F. Gonzalez-Serrano, V. Pirro, C.R. Ferreira, P. Oliveri, L.S. Eberlin, J. Heinzmann, A. Lucas-Hahn, H. Niemann and R.G. Cooks, 鈥淒esorption Electrospray Ionization Reveals Lipid Metabolism of Individual Oocytes and Embryos鈥, PloS ONE, 2013, 8, e74981.
- L.S. Eberlin, I. Norton, A.L. Dill, A.J. Golby, K.L. Ligon, S. Santagata, R.G. Cooks and N.Y.R. Agar, "Classifying Human Brain Tumors by Lipid Imaging with Mass Spectrometry", Cancer Research, 2012, 72, 645-654.
- A.K. Badu-Tawiah, L.S. Eberlin, Z. Ouyang and R.G. Cooks, "Chemical Aspects of the Extractive Methods of Ambient Ionization Mass Spectrometry", Annual Review of Analytical Chemistry, 2013, 64,481-505.
- C.R. Ferreira, V. Pirro, L.S. Eberlin, J.E. Hallett and R.G. Cooks, "Developmental Phases in Individual Mouse Preimplantation Embryos Characterized by Lipid Signatures in Desorption Electrospray Ionization Mass Spectrometry", Analytical and Bioanalytical Chemistry, 2012, 404, 2915-2926.
101. D.I. Campbell, C.R. Ferreira, L.S. Eberlin, R.G. Cooks, "Improved spatial resolution in the imaging of biological tissue using desorption electrospray ionization", Analytical and Bioanalytical Chemistry, 2012, 404, 389 -398. - X. Xiong, W. Xu, L.S. Eberlin, J.M. Wiseman, X.Fang, Y. Jiang, Z. Huang, Y. Zhang, R.G. Cooks, Z. Ouyang, 鈥淒ata processing for 3D mass spectrometry imaging鈥, Journal of the American Society of Mass Spectrometry, 2012, 23, 1147 - 1156.
- V. Pirro, L.S. Eberlin, P. Oliveri, R.G. Cooks, 鈥淚nteractive hyperspectral approach for exploring and interpreting DESI-MS images of cancer and normal tissue sections鈥, Analyst, 2012, 137, 2374 - 2380.
- C.R. Ferreira, L.S. Eberlin, J.E. Hallett, R.G. Cooks, "Single oocyte and single embryo lipid analysis by desorption electrospray ionization mass spectrometry", Journal of Mass Spectrometry, 2012, 47, 28-32.
105. L.S. Eberlin, X. Liu, C.R. Ferreira, S. Santagata, N.Y.R. Agar, R.G. Cooks, "Desorption electrospray ionization then MALDI mass spectrometry imaging of lipid and protein distributions in single tissue sections", Analytical Chemistry, 2011, 83, 8366-8371. - L.S. Eberlin, C.R. Ferreira, A.L. Dill, L.Cheng and R.G. Cooks, "Non-Destructive, Histologically Compatible Tissue Imaging by Desorption Electrospray Ionization Mass Spectrometry", ChemBioChem, 2011, 12, 2129 -2132.
- A.L. Dill, L.S. Eberlin, A.B. Costa, D.R. Ifa, R.G. Cooks, "Data Quality in Tissue Analysis using Desorption Electrospray Ionization", Analytical and Bioanalytical Chemistry, 2011, 401, 1949 -1961.
- L.S. Eberlin, C.R. Ferreira, A.L. Dill, D.R. Ifa, R.G. Cooks, 鈥淒esorption Electrospray Ionization Mass Spectrometry for Lipid Characterization and Biological Tissue Imaging鈥, Biochimica et Biophysica Acta Molecular and Cell Biology of Lipids, 2011, 1811, 946 -960.
- T.A. Masterson, A.L. Dill, L.S. Eberlin, M.Mattarozzi, L. Cheng, S.D. W. Beck, F. Bianchi, R.G. Cooks, "Distinctive Glycerophospholipid Profiles of Human Seminoma and Adjacent Normal Tissues by Desorption Electrospray Ionization Imaging Mass Spectrometry", Journal of the American Society of Mass Spectrometry, 2011, 22, 1326-1333.
- D.R. Ifa, A. Srimany, L.S. Eberlin, H.R. Naik, V. Bhat, R.G. Cooks, T. Pradeep, "Tissue Imprint Imaging by Desorption Electrospray Ionization Mass Spectrometry", Analytical Methods, 2011, 3, 1910-1912.
- A.L. Dill, L.S. Eberlin, A.B. Costa, C. Zheng, D.R. Ifa, L. Cheng, T.A. Masterson, M.O. Koch, O. Vitek, and R.G. Cooks, "Statistical Classification of Human Bladder Carcinomas using Ambient Ionization Imaging Mass Spectrometry", Chemistry-A European Journal, 2011, 17, 2897鈥2902.
- L.S. Eberlin, A.L. Dill, A.J. Golby, K.L. Ligon, J.M. Wiseman, R.G. Cooks, N.Y. R. Agar, "Discrimination of Human Astrocytoma Subtypes by Lipid Analysis using Desorption Electrospray Ionization Imaging Mass Spectrometry", Angewandte Chemie International Edition, 2010, 49, 5953-5956.
- L.S. Eerlin, R. Haddad, R.C.S. Neto, R.G. Cosso, D.R.J. Maia, A.O. Maldaner, J.J. Zacca, G.B. Sanvido, W. Romao, B.G. Vaz, D.R. Ifa, A.L. Dill, R.G. Cooks, M.N. Eberlin, 鈥淚nstantaneous Chemical Profiles of Banknotes by Ambient Mass Spectrometry鈥, Analyst, 2010, 135, 2533-2539.
- A.L. Dill, L.S. Eberlin, C. Zheng; A.B. Costa; D.R. Ifa; L. Cheng; T.A. Masterson; M.O. Koch; O. Vitek; R.G. Cooks, "Statistical Differentiation of Renal Cell Carcinomas based on Lipidomic Analysis by Ambient Ionization Imaging Mass Spectrometry", Analytical and Bioanalytical Chemistry, 2010, 398, 2969-2978.
- R.G. Cooks, N.E. Manicke, A.L. Dill, D.R. Ifa, L.S. Eberlin, A.B. Costa, H. Wang, G. Huang, Z. Ouyang, "New ionization methods and miniature mass spectrometers in biomedicine: DESI imaging for cancer diagnostics and paper spray ionization for therapeutic drug monitoring", Faraday Discussions, 2010, 149, 247-267.
- L.S. Eberlin, A.L. Dill, A.B. Costa, D.R. Ifa, L.Cheng, T.Masterson, M.Koch, T.L. Ratliff, and R.G. Cooks, "Cholesterol Sulfate Imaging in Human Prostate Cancer Tissue by Desorption Electrospray Ionization Mass Spectrometry", Analytical Chemistry, 2010, 82, 3430-3434.
- L.S. Eberlin, D.R. Ifa, C.Wu, R.G. Cooks, "Three-Dimensional Visualization of Mouse Brain by Lipid Analysis Using Ambient Ionization Mass Spectrometry", Angewandte Chemie International Edition, 2010, 49, 873-876.
- A.L. Dill, L.S. Eberlin, D.R. Ifa and R.G. Cooks, "Perspectives in Imaging using Mass Spectrometry", Chemical Communications, 2010, 47, 2741 -2746.
- P. Albors, L.D. Slep, L.S. Eberlin, Y.E. Corilo, M.N. Eberlin, G. Bentez, M.E. Vela, R.C. Salvarezza and L.M. Baraldo, "From Monomers to Geometry-Constrained Molecules: One Step Further Toward Cyanide Bridged Wires", Inorganic Chemistry, 2009, 48, 11226-11235.
- L.S. Eberlin, P.V. Abdelnur, A. Passero, G.F. de Sa, R.J. Daroda, V. Souza and M.N. Eberlin, "Analysis of biodiesel and biodiesel鈥損etrodiesel blends by high performance thin layer chromatography combined with easy ambient sonic-spray ionization mass spectrometry", Analyst, 2009, 134, 1652-1657.
- L.S. Eberlin, Y. Xia, H. Chen and R.G. Cooks, "Atmospheric Pressure Thermal Dissociation of Phospho- and Sulfopeptides", Journal of the American Society of Mass Spectrometry, 2008, 19, 1897-1905.
- P.V. Abdelnur, L.S. Eberlin, G.F. de S谩, V.Souza and M.N. Eberlin, "Single-Shot Biodiesel analysis: Nearly Instanteneous Typification and Quality Control Solely by Ambient Mass Spectrometry", Analytical Chemistry, 2008, 80, 7882-7886.
- M. Benassi, L.A.B. Moraes, L.G. Cabrini, L.C. Dias, A.M. Aguilar, G.A. Romeiro, L.S. Eberlin, M.N. Eberlin. "Recognition of cyclic, acyclic, exocyclic, spiro acetals via structurally diagnostic ion/molecule reactions with the (CH3)2N-C+=O acylium ion", Journal of Organic Chemistry, 2008, 73, 5549-5557.
- H. Chen, L.S. Eberlin, M. Nefliu, R. Augusti, R.G. Cooks, "Organic Reactions of Ionic Intermediates Promoted by Atmospheric-Pressure Thermal Activation", Angewandte Chemie International Edition, 2008, 47, 3422-3425.
- H. Chen, L.S. Eberlin and R.G. Cooks, "Neutral Fragment Mass Spectra after Ambient Thermal Dissociation of Peptide and Protein Ions", Journal of the American Chemical Society, 2007, 129, 5880-5886.
- D.R. Ifa, L. Gumaelius, L.S. Eberlin, N.E. Manicke and R.G. Cooks, "Forensic Analysis of Inks by Imaging Desorption Electrospray Ionization Mass Spectrometry", Analyst, 2007, 132, 461-467.
- A.H. Junior, L. Firn, A.J. Bortoluzzi, B.Szpoganicz, M.S. Silva, M.A. Novak, M.B. Neto, L.S. Eberlin, R.R. Catharino, M.N. Eberlin, C.Fernandes. "Solid state and solution characterization of a new dinuclear nickel (II) complex: The search for synthetic models for urease", Journal of Molecular Structure, 2006, 797, 154-164.
- R. Sparrapan, L.S. Eberlin, R. Haddad, R.G. Cooks, M.N. Eberlin and R. Augusti, "Ambient Eberlin Reactions via Desorption Electrospray Ionization", Journal of Mass Spectrometry, 2006, 41, 1242 -1264.
- R. Augusti, H. Chen, L.S. Eberlin, M. Nefliu and R.G. Cooks, "Atmospheric pressure Eberlin transacetalization reactions in the heterogeneous liquid/gas phase", International Journal of Mass Spectrometry, 2006, 253, 281-287.