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Sujith K Joseph

Joseph

Sujith K Joseph, Ph.D.

Assistant Professor

(832) 824-6836

Email

sujith.joseph@bcm.edu

Positions

Assistant Professor
Departments of Pediatrics
Hematology-Oncology Cell & Gene Therapy
ÌÇÐÄÊÓƵ of Medicine
Houston, Texas, United States

Education

Postdoctoral Fellowship at National Institutes of Health
Bethesda, United States
Immunology and Vaccinology
Postdoctoral Fellowship at University of Illinois College of Medicine
Rockford, Illinois, United States
Immunology and Vaccine development
PhD from CSJM University & Central Drug Research Institute
Lucknow, India
Life Sciences

Professional Interests

  • Novel chimeric antigen receptor (CAR) T cells for solid tumors
  • Correlates of immune response - CAR T cell clinical trials
  • Synthetic cell receptors for tumor immunotherapy

Professional Statement

I am a scientist trained in human immunology of prophylactic and therapeutic interventions. I conduct translational research with gene-modified T-cells for solid tumors in children and young adults. My focus is on development of synthetic receptor molecules including chimeric antigen receptor (CAR) and delineating immune responses in patients undergoing CAR T-cell therapy in clinical trials.

Websites

Selected Publications

  • Konduri V, Joseph SK, Byrd TT, Nawas Z, Vazquez-Perez J, Hofferek CJ, Halpert MM, Liu D, Liang Z, Baig Y, Salsman VS, Oyewole-Said D, Tsimelzon A, Burns BA, Chen C, Levitt JM, Yao Q, Ahmed NM, Hegde M, Decker WK. " " Sci Transl Med. 2021 May ; (13(592)) : eabc3196.
    Pubmed PMID: .
  • Fousek K, Watanabe J, Joseph SK, George A, An X, Byrd TT, Morris JS, Luong A, Martínez-Paniagua MA, Sanber K, Navai SA, Gad AZ, ......, Jang A, Baker ML, Varadarajan N, Hegde M, Kim YM, Heisterkamp N, Abdel-Azim H, Ahmed N. " " Leukemia. 2021 ; 35 (1) : 75-89.
    Pubmed PMID: .
  • Donovan LK, Delaidelli A, Joseph SK, Bielamowicz K, Fousek K, Holdago, BL, et al. Manno A, Srikanthan D, ......., Maris JM, Sorensen PHB, Ahmed N, Taylor MD.. " " Nat Med.. 2020 ; 26 (5) : 720-731.
    Pubmed PMID: .
  • Hegde M, Joseph SK, Pashankar F, LoRenzo D, Khaled S, Byrd, T, Navai S, Hicks MJ, Xu, M, Gerken C, Patricia K; Perera CS, Zhang H, Shree A, Dakhova O, Brawley VS, Grilley BJ, Gee A, Dotti P, Heslop HE, Brenner MK, Wels W, Gottschalk S, Ahmed N. " " Nat Commun. 2020 ; 11 (1) : 3549.
    Pubmed PMID: .

Memberships

American Society of Gene & Cell Therapy
Member
Society for Immunotherapy of Cancer
Member
Dan L Duncan Comprehensive Cancer Center
Associate Member
Gulf Coast Consortia
Member

Funding

Developing Sarcoma-specific T-cell Platform for Grafting Chimeric Antigen Receptors
Grant funding from The Faris Foundation Immunotherapy Award
Research Award
Grant funding from Sarcoma Foundation of America
Targeting High-Risk Medulloblastoma Using Locally-Delivered Endoglin CAR-T
Grant funding from Rally Foundation for Childhood Cancer Research Career Development Award
Cell Engineering to Improve CAR-T Cell Therapy for Pediatric Sarcomas
Grant funding from VICTORY Houston Inc.

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