Qian Zhu, Ph.D.
Assistant Professor
Positions
- Assistant Professor
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Lester and Sue Smith Breast Center
Department of Molecular Genetics
ÌÇÐÄÊÓƵ of Medicine
Houston, US
Addresses
- BCM Jewish Building (Office)
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Room 644D
Houston, TX, 77030
United States
qian.zhu@bcm.edu
Education
- BSc from University of Ottawa
- Ottawa, Ontario, Canada
- PhD from Princeton University
- Princeton, New Jersey, United States
- Postdoctoral Training at Dana-Farber Cancer Institute/Harvard Medical School
- Boston, Massachusetts, United States
Honors & Awards
- 2025 recipient of the Marion R. Wright Award for Scientific Excellence
- Breast Cancer Research Foundation
- Baylor Genetics Service Awards, Best Papers of 2025
- ÌÇÐÄÊÓƵ of Medicine (01/2026)
Professional Interests
- Bioinformatics
- Computational genomics
- Cancer biology
Professional Statement
Dr. Qian Zhu is interested in the development of computational methods for genomic technologies that are being applied in cancer research. His previous works include: smfishHMRF, a hidden-Markov random field model for single-molecule FISH; Giotto, a comprehensive package for spatial transcriptomic analyses; CUT&RUNTools, a tool for CUT&RUN data processing and motif footprinting prediction. These tools are being applied to data to better understand the sources of intra-tumor heterogeneity, tumor-immune cross-talk, and reveal novel image-based and genomic biomarkers that are predictive of clinical outcomes. He works closely with experimental collaborators and contributes in a collaborative team to understand mechanisms underlying tumor progression and therapy resistance. Recently, he is interested in developing methods in the area of spatial transcriptomics, and working on improving the integration of machine learning algorithms in histopathology imaging analyses. He is also interested in large-scale data visualization approaches and developing databases/portals to improve the access of genomics information for patients and clinicians.
Websites
Selected Publications
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Ruben Dries*, Qian Zhu*, Rui Dong, Chee-Huat Linus Eng, Huipeng Li, Kan Liu, Yuntian Fu, Tianxiao Zhao, Arpan Sarkar, Feng Bao, Rani E. George, Nico Pierson, Long Cai & Guo-Cheng Yuan. " " Genome Biol.. 2021 ;
Pubmed PMID: . -
Qian Zhu, Nan Liu, Stuart H Orkin, Guo-Cheng Yuan. " " Genome Biol.. 2019 ;
Pubmed PMID: . -
Qian Zhu, Sheel Shah, Ruben Dries, Long Cai, Guo-Cheng Yuan. " " Nat Biotechnol.. 2018 ; 36 : 1183-1190.
Pubmed PMID: . -
Qian Zhu, Aaron K Wong, Arjun Krishnan, Miriam R Aure, Alicja Tadych, Ran Zhang, David C Corney, Casey S Greene, Lars A Bongo, Vessela N Kristensen, Moses Charikar, Kai Li, and Olga G. Troyanskaya. " " Nat Methods. 2015 ; 12 (3) : 211-214.
Pubmed PMID: .
Memberships
- Intelligent Systems for Molecular Biology Conference
- American Association for Cancer Research
Funding
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Recruitment of First-Time, Tenure-Track Faculty Members
- CPRIT
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