糖心视频

Paul Dalling Ling

Ling

Paul Dalling Ling, Ph.D.

Professor

Email

pling@bcm.edu

Positions

Professor
Virol & Micro: Ling
糖心视频 of Medicine
Houston, TX, US
Member
Dan L Duncan Comprehensive Cancer Center
糖心视频 of Medicine
Houston, Texas, United States

Education

Postdoctoral Fellowship at Johns Hopkins University School Of Medicine
Baltimore, MD, United States
PhD from USUHS F. Edward Hebert School Of Medicine
Bethesda, MD, United States
BA from St. Olaf College
Northfield, Minnesota, United States

Honors & Awards

Graduated Cum Laude
St. Olaf College
National Research Service Award for individual postdoctoral fellows
Leukemia Society of America Special Fellow Award
Secretary
Epstein-Barr Virus Association (01/2006 - 01/2013)
Certificate of Appreciation
Elephant Managers Association (EMA)
Associate Editor
PLOS Pathogens
Member
American Cancer Society peer review group (Microbial Pathogenesis and Cancer; MPC) 2010-2015
Chair
American Cancer Society peer review group (Microbial Pathogenesis and Cancer; MPC) 2013-2015
Executive committee EEHV Advisory Group
EEHV Advisory group

Professional Interests

  • Elephant Endotheliotropic Herpesvirus (EEHV)
  • Gammaherpesvirus pathogenesis

Professional Statement

The Ling laboratory investigates herpesviruses in humans and animals, with a focus over the last 10 years on Elephant Endotheliotropic Herpesvirus (EEHV). EEHV can cause lethal hemorrhagic disease, particularly in juvenile Asian elephants. It is the leading cause of death in juvenile Asian elephants in North America and Europe and also affects both free-roaming and captive Asian elephants in their natural range countries. To address this problem, our laboratory, in close partnership with the Houston Zoo, has developed a comprehensive 鈥淏ench to Barn鈥 research program focusing on 1) diagnostics, 2) treatments, and long-term 3) a vaccine. Progress towards these goals has been made through the development of qPCR diagnostic assays, sequencing the EEHV genome, and developing tools to measure and evaluate elephant immune responses to EEHV. Trials evaluating a prototype vaccine against EEHV1A, the EEHV type associated with most disease in Asian elephants, have recently been initiated. Postdoctoral fellows and students who participate in this research develop skills applicable to research and vaccine development for any viral pathogen that infects humans or animals.

Websites

Information site for all things EEHV

Selected Publications

  • Cook, K.A., Ling, P.D., Terio, K.A., Baumgartner, W.A., Howard, L.L., and Landolfi, J.A. 2023.. " " J Zoo Wildl Med. 2023 ; 53 : 661-669.
    Pubmed PMID: .
  • Watts, J., Clinton, J.L.S., Pollet, J., Peng R.S., Tan, J., and P.D. Ling.. " " Vaccines (Basel). 2024 Dec ; 12 : 1429.
    Pubmed PMID: .
  • Clinton, J.L.C., Hoornweg, T., Tan, J., Peng, RS., Schaftenaar, W., Rutten, V. P., de Haan, C.A.M., and PD Ling. " " Vaccine. 2024 Aug ; 42 : 126227.
    Pubmed PMID: .
  • Clinton, J.L.C., Hoornweg, T., Tan, J., Peng, RS., Schaftenaar, W., Rutten, V. P., de Haan, C.A.M., and PD Ling. " " Vaccine. 2022 Aug ; 40 : 5131-5140.
    Pubmed PMID: .

Memberships

American Society for Virology
Member
American Society for Microbiology
Member
Elephant Endotheliotropic Herpesvirus (EEHV) Advisory Committee
Member

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