O Howard Frazier

O Howard Frazier, M.D.

Professor of Surgery

(832) 355-2285

Email

ofrazier@texasheart.org

Positions

Professor of Surgery: Cardiothoracic Transplantation & Circulatory Support
��Ƶ of Medicine
Houston, TX, US

Chief, Center for Cardiac Support: Baylor St. Luke's Medical Center

Chief, Cardiopulmonary Transplantation: Texas Heart Institute

Program Director and Chief, Center for Cardiac Support: Texas Heart Institute

Director, Surgical Research, Cullen Cardiovascular Research Laboratories: Texas Heart Institute

Addresses

Baylor St. Luke's Medical Center (Hospital): 6720 Bertner Ave.
Room: LUKE-2-114A
Houston, TX, 77030
United States

Education

Residency at ��Ƶ of Medicine: 01/1974 - Houston, TX, United States

BS from University of Texas at Austin: 01/1963 - Austin, TX, United States

MD from ��Ƶ of Medicine: 01/1967 - Houston, TX, United States

Residency at ��Ƶ of Medicine: 01/1968 - Houston, TX, United States; General Surgery

Fellowship at Texas Heart Institute - ��Ƶ of Medicine: 01/1976 - Houston, TX, United States; Thoracic Surgery

Certifications

Thoracic Surgery: American Board of Thoracic Surgery

General Surgery: American Board of Surgery

Honors & Awards

2009 Best of the Best: Medical Journal Houston

Houston’s Top Docs - Physicians Who May One Day Save Your Life”: Inside Houston

The Country's Best Heart Doctors": Good Housekeeping Magazine

Wilhelm Scholê International Cosmopolis Award

Ray C. Fish Award for Scientific Achievement: Texas Heart Institute

America’s Top Doctors: Castle Connolly

Living Legend Award: World Society of Cardiothoracic Surgeons

America’s Top Doctors: Newsweek Magazine

First Annual “Gift to Mankind” Award: American Organ Transplant Association

Best Doctors in America

The Best Medical Specialists in North America: Town & Country

2021 Scientific Achievement Award: American Association for Thoracic Surgery

ASAIO Lifetime Achievement Award: American Society for Artificial Internal Organs

Professional Interests

Professional Statement

For more than 30 years, Dr. O. H. Frazier has been a pioneer in the treatment of severe heart failure and in the fields of heart transplantation and artificial devices that may be used either to substitute for or assist the pumping action of the human heart. As a result of his work, the Texas Heart Institute has become one of the top transplantation and mechanical circulatory support programs in the world. Dr. Frazier has performed over 1,200 heart transplants and implanted more than 900 left ventricular assist devices, more than any other surgeon in the world.

Dr. Frazier’s interest in mechanical circulatory support began in 1969, when, as a student at ��Ƶ of Medicine, he wrote a research paper about the experimental total artificial heart, which was first implanted in 1969 by Dr. Denton Cooley. Throughout the 1970s and 1980s, Dr. Frazier continued experimental work toward developing an implantable left ventricular assist device (LVAD) to aid the failing heart. In 2011, Dr. Frazier implanted the first successful continuous-flow total artificial heart using two second generation HeartMate II LVADs to replace a patient’s failing heart.

Websites

VIICTR Research Database

Dr. O. Howard Frazier Named William W. L. Glenn Lecturer and Award Recipient

Dr. Frazier Presented with Lifetime Awards

Videos

Dr. Bud Frazier - Pioneering a New Frontier

Selected Publications

Park SJ, Tector A, Piccioni W, Raines E, Gelijns A, Moskowitz A, Rose E, Holman W, Furukawa S, Frazier OH, Dembitsky W. " " J. Thorac. Cardiovasc. Surg.. 2005 Jan ; 129 (1) : 41534.
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Undar A, Henderson N, Thurston GB, Masai T, Beyer EA, Frazier OH, Fraser CD. " " Artif Organs. 1999 Aug ; 23 (8) : 717-21.
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Slaughter MS, Rogers JG, Milano CA, Russell SD, Conte JV, Feldman D, Sun B, Tatooles AJ, Delgado RM, Long JW, Wozniak TC, Ghumman W, Farrar DJ, Frazier OH. " " N. Engl. J. Med.. 2009 Dec 3; 361 (23) : 2241-51.
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Pagani FD, Miller LW, Russell SD, Aaronson KD, John R, Boyle AJ, Conte JV, Bogaev RC, MacGillivray TE, Naka Y, Mancini D, Massey HT, Chen L, Klodell CT, Aranda JM, Moazami N, Ewald GA, Farrar DJ, Frazier OH. " " J. Am. Coll. Cardiol.. 2009 Jul 21; 54 (4) : 312-21.
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Moazami N, Milano CA, John R, Sun B, Adamson RM, Pagani FD, Smedira N, Slaughter MS, Farrar DJ, Frazier OH. " " Ann. Thorac. Surg.. 2013 Feb ; 95 (2) : 500-5.
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Griffith BP, Anderson MB, Samuels LE, Pae WE, Naka Y, Frazier OH. " " J. Thorac. Cardiovasc. Surg.. 2013 Feb ; 145 (2) : 548-54.
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Rose AG, Connelly JH, Park SJ, Frazier OH, Miller LW, Ormaza S. " " J. Heart Lung Transplant.. 2003 May ; 22 (5) : 594-9.
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Chandra D, Kar B, Idelchik G, Simpson L, Loyalka P, Gregoric ID, Delgado RM, Frazier OH. " " Am. J. Cardiol.. 2007 Jun 15; 99 (12) : 1755-6.
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Gajarski RJ, Smith EO, Denfield SW, Rosenblatt HM, Kearney D, Frazier OH, Radovancevic B, Price JK, Kertesz NJ, Towbin JA. " " Transplantation. 1998 Jun 15; 65 (11) : 1470-6.
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Undar A, Masai T, Yang SQ, Goddard-Finegold J, Frazier OH, Fraser CD. " " Ann. Thorac. Surg.. 1999 Oct ; 68 (4) : 1336-42; discus.
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Flamm SD, Walmsley R, Frazier OH. " " Circulation. 2002 Feb 5; 105 (5) : E36-6.
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Wu JT, Frazier OH, Nasser MM, Reul RM. " " Innovations (Phila). 2010 Sep ; 5 (5) : 364-8.
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Shaffer KM, Denfield SW, Schowengerdt KO, Towbin JA, Radovancevic B, Frazier OH, Price JK, Gajarski RJ. " " Tex Heart Inst J. 1998 ; 25 (1) : 57-63.
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Cooley DA, Frazier OH, Kahan BD. " " Tex Heart Inst J. 1982 Sep ; 9 (3) : 247-51.
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Okereke OU, Frazier OH, Cooley DA, Waldenberger F, Radovancevic B. " " Tex Heart Inst J. 1984 Sep ; 11 (3) : 228-32.
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Painvin GA, Reece IJ, Cooley DA, Frazier OH. " " Tex Heart Inst J. 1983 Dec ; 10 (4) : 371-86.
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Shah NR, Lam WW, Rodriguez FH, Ermis PR, Simpson L, Frazier OH, Franklin WJ, Parekh DR. " " J. Heart Lung Transplant.. 2013 Jun ; 32 (6) : 615-20.
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Bogaev RC, Pamboukian SV, Moore SA, Chen L, John R, Boyle AJ, Sundareswaran KS, Farrar DJ, Frazier OH. " " J. Heart Lung Transplant.. 2011 May ; 30 (5) : 515-22.
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Takach TJ, Reul GJ, Duncan JM, Krajcer Z, Livesay JJ, Gregoric ID, Cervera RD, Ott DA, Frazier OH, Cooley DA. " " Ann. Thorac. Surg.. 2005 Aug ; 80 (2) : 564-9.
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Archer R, Ott DA, Parravicini R, Cooley DA, Reul GJ, Frazier OH, Duncan JM, Livesay JJ, Walker WE. " " Tex Heart Inst J. 1984 Mar ; 11 (1) : 52-7.
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Torre-Amione G, Stetson SJ, Youker KA, Durand JB, Radovancevic B, Delgado RM, Frazier OH, Entman ML, Noon GP. " " Circulation. 1999 Sep 14; 100 (11) : 1189-93.
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Undar A, Frazier OH, Fraser CD. " " Artif Organs. 1999 Aug ; 23 (8) : 712-6.
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Bruckner BA, Razeghi P, Stetson S, Thompson L, Lafuente J, Entman M, Loebe M, Noon G, Taegtmeyer H, Frazier OH, Youker K. " " J. Heart Lung Transplant.. 2004 Jan ; 23 (1) : 36-42.
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Westaby S, Siegenthaler M, Beyersdorf F, Massetti M, Pepper J, Khayat A, Hetzer R, Frazier OH. " " Eur J Cardiothorac Surg. 2010 Feb ; 37 (2) : 350-6.
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Razeghi P, Young ME, Cockrill TC, Frazier OH, Taegtmeyer H. " " Circulation. 2002 Jul 23; 106 (4) : 407-11.
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Walker WE, Duncan JM, Frazier OH, Livesay JJ, Ott DA, Reul GJ, Cooley DA. " " J. Thorac. Cardiovasc. Surg.. 1983 Oct ; 86 (4) : 570-5.
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Scheinin SA, Radovancevic B, Kimball P, Duncan JM, Van Buren CT, Frazier OH, Kerman R. " " Tex Heart Inst J. 1995 ; 22 (1) : 67-71.
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Undar A, Masai T, Inman R, Beyer EA, Mueller MA, McGarry MC, Frazier OH, Fraser CD. " " ASAIO J.. ; 45 (1) : 53-8.
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Reece IJ, Painvin GA, Okereke OU, Chandler LB, Krudewig TW, Igo SR, Cooley DA, Frazier OH. " " Tex Heart Inst J. 1984 Mar ; 11 (1) : 38-42.
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Kearney DL, Towbin JA, Bricker JT, Radovancevic B, Frazier OH. " " Pediatr Pathol Lab Med. ; 15 (1) : 181-9.
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Bick RJ, Bagwell SH, Jones CE, Poindexter BJ, Buja LM, Youker KA, Grigore A, Clubb F, Radovancevic B, Frazier OH. " " J. Heart Lung Transplant.. 2005 Apr ; 24 (4) : 454-61.
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Sen S, Kundu BK, Wu HC, Hashmi SS, Guthrie P, Locke LW, Roy RJ, Matherne GP, Berr SS, Terwelp M, Scott B, Carranza S, Frazier OH, Glover DK, Dillmann WH, Gambello MJ, Entman ML, Taegtmeyer H. " " J Am Heart Assoc. 2013 ; 2 (3) : e004796.
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Undar A, Koenig KM, Frazier OH, Fraser CD. " " Perfusion. 2000 Mar ; 15 (2) : 111-20.
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Chilukuri S, Herlihy JP, Massumkhani GA, Duncan JM, Frazier OH. " " Ann. Thorac. Surg.. 2001 Jul ; 72 (1) : 261-3.
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Ott DA, Parravacini R, Cooley DA, DePuey EG, Reul GJ, Duncan JM, Frazier OH, Livesay JJ. " " Tex Heart Inst J. 1982 Sep ; 9 (3) : 267-73.
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Bourque K, Dague C, Farrar D, Harms K, Tamez D, Cohn W, Tuzun E, Poirier V, Frazier OH. " " Artif Organs. 2006 Aug ; 30 (8) : 638-42.
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Ballantyne CM, Masri BM, Clubb FJ, Radovancevic B, Smith CW, Hawkins HK, Frazier OH, Willerson JT. " " Tex Heart Inst J. 1996 ; 23 (4) : 293-5.
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Reece IJ, Painvin GA, Chandler LB, Gentry BL, Zeluff B, Okereke OU, Cooley DA, Frazier OH. " " Tex Heart Inst J. 1984 Mar ; 11 (1) : 32-7.
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Uray IP, Connelly JH, Thomázy V, Shipley GL, Vaughn WK, Frazier OH, Taegtmeyer H, Davies PJ. " " J. Heart Lung Transplant.. 2002 Jul ; 21 (7) : 771-82.
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Gajarski RJ, Towbin JA, Bricker JT, Radovancevic B, Frazier OH, Price JK, Schowengerdt KO, Denfield SW. " " J. Am. Coll. Cardiol.. 1994 Jun ; 23 (7) : 1682-7.
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Bick RJ, Grigore AM, Poindexter BJ, Schnee PM, Nussmeier NA, Gregoric ID, Shah NA, Myers TJ, Buja LM, Frazier OH. " " J Card Surg. ; 20 (4) : 332-6.
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Favor A, Frazier OH, Cooley DA, Okereke OU, Radovancevic B, Powers P, Chandler L. " " Tex Heart Inst J. 1985 Jun ; 12 (2) : 153-6.
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Schnee PM, Shah N, Bergheim M, Poindexter BJ, Buja LM, Gemmato C, Radovancevic B, Letsou GV, Frazier OH, Bick RJ. " " J. Heart Lung Transplant.. 2008 Jul ; 27 (7) : 710-7.
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Westaby S, Frazier OH. " " Eur J Cardiothorac Surg. 2012 Aug ; 42 (2) : 203-8.
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Boyle AJ, Russell SD, Teuteberg JJ, Slaughter MS, Moazami N, Pagani FD, Frazier OH, Heatley G, Farrar DJ, John R. " " J. Heart Lung Transplant.. 2009 Sep ; 28 (9) : 881-7.
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Kassiotis C, Ballal K, Wellnitz K, Vela D, Gong M, Salazar R, Frazier OH, Taegtmeyer H. " " Circulation. 2009 Sep 15; 120 (11) : S191-7.
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Uray IP, Connelly JH, Frazier OH, Taegtmeyer H, Davies PJ. " " Cardiovasc. Res.. 2003 Jul 1; 59 (1) : 57-66.
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Undar A, Eichstaedt HC, Frazier OH, Fraser CD. " " ASAIO J.. ; 46 (1) : 103-6.
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Martin AB, Bricker JT, Fishman M, Frazier OH, Price JK, Radovancevic B, Louis PT, Cabalka AK, Gelb BD, Towbin JA. " " J. Heart Lung Transplant.. ; 11 (5) : 933-42.
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Louis PT, Bricker JT, Frazier OH, Duncan M, Towbin JA, Gelb BD, Macris MA, Radovencavic B, Kearney D, Igo S. " " Crit. Care Med.. 1992 May ; 20 (5) : 704-7.
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Westaby S, Banning A, Neil D, Poole-Wilson P, Frazier OH. " " J. Thorac. Cardiovasc. Surg.. 2010 Mar ; 139 (3) : e45-7.
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John R, Long JW, Massey HT, Griffith BP, Sun BC, Tector AJ, Frazier OH, Joyce LD. " " J. Thorac. Cardiovasc. Surg.. 2011 Apr ; 141 (4) : 932-9.
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Morales DL, Dreyer WJ, Denfield SW, Heinle JS, McKenzie ED, Graves DE, Price JF, Towbin JA, Frazier OH, Cooley DA, Fraser CD. " " J. Thorac. Cardiovasc. Surg.. 2007 Mar ; 133 (3) : 632-9.
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Radovancevic R, Bracey AW, Radovancevic B, Elayda M, Gregoric ID, Frazier OH. " " Artif Organs. 2008 Jun ; 32 (6) : 427-32.
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John R, Pagani FD, Naka Y, Boyle A, Conte JV, Russell SD, Klodell CT, Milano CA, Rogers J, Farrar DJ, Frazier OH. " " J. Thorac. Cardiovasc. Surg.. 2010 Jul ; 140 (1) : 174-81.
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Cabalka AK, Rosenblatt HM, Towbin JA, Price JK, Windsor NT, Martin AB, Louis PT, Frazier OH, Bricker JT. " " Tex Heart Inst J. 1995 ; 22 (2) : 170-6.
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Undar A, Masai T, Frazier OH, Fraser CD. " " ASAIO J.. ; 45 (6) : 610-4.
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Scolletta S, Gregoric ID, Muzzi L, Radovancevic B, Frazier OH. " " Perfusion. 2007 Jan ; 22 (1) : 63-6.
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Cooley DA, Frazier OH. " " Tex Heart Inst J. 1983 Mar ; 10 (1) : 71-5.
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Schnee PM, Shah N, Bergheim M, Poindexter BJ, Buja LM, Myers TJ, Radovancevic B, Frazier OH, Bick RJ. " " MedGenMed. 2006 ; 8 (2) : 45.
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Vasiljevic JD, Otasevic P, Popovic ZB, Neskovic AN, Vidakovic R, Popovic ZV, Radovancevic B, Frazier OH, Gradinac S. " " Eur. J. Heart Fail.. 2005 Aug ; 7 (5) : 763-7.
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Bruckner BA, Stetson SJ, Farmer JA, Radovancevic B, Frazier OH, Noon GP, Entman ML, Torre-Amione G, Youker KA. " " Am. J. Surg.. 2000 Dec ; 180 (6) : 498-501; discus.
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Mulvagh SL, Thornton B, Frazier OH, Radovancevic B, Norton HJ, Noon GP, Young JB. " " Circulation. 1989 Nov ; 80 (5) : III126-32.
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Duncan JM, Cooley DA, Livesay JJ, Ott DA, Reul GJ, Walker WE, Frazier OH. " " Tex Heart Inst J. 1983 Mar ; 10 (1) : 41584.
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Ventemiglia RA, Oglietti J, Izquierdo J, Muasher I, Frazier OH, Cooley DA. " " Tex Heart Inst J. 1983 Mar ; 10 (1) : 31-7.
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Razeghi P, Buksinska-Lisik M, Palanichamy N, Stepkowski S, Frazier OH, Taegtmeyer H. " " FASEB J.. 2006 Jun ; 20 (8) : 1090-6.
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Shah NR, Cevik C, Hernandez A, Gregoric ID, Frazier OH, Stainback RF. " " J. Card. Fail.. 2012 Sep ; 18 (9) : 745-8.
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Agusala K, Bogaev R, Frazier OH, Franklin WJ. " " Congenit Heart Dis. 2010 Nov ; 5 (6) : 635-7.
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Goldstein DJ, Maybaum S, Macgillivray TE, Moore SA, Bogaev R, Farrar DJ, Frazier OH. " " J. Card. Fail.. 2012 May ; 18 (5) : 392-5.
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Memberships

American College of Cardiology: Fellow

American College of Surgeons: Fellow

Denton A. Cooley Cardiovascular Surgical Society

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