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Kathleen J Motil

Motil

Kathleen J Motil, M.D., Ph.D.

Distinguished Professor Emeritus

(832) 822-3131

Positions

Distinguished Professor Emeritus
Pediatrics-Gastroenterology, Hepatology, & Nutrition
ÌÇÐÄÊÓÆµ of Medicine
Houston, TX, US

Addresses

Texas Children's Clinical Care Center (Clinic)
Pediatric Gastroenterology, Hepatology and Nutrition
6701 Fannin St.
Houston, TX, 77030
United States
Phone: (832) 822-3131
Children's Nutrition Research Center (Office)
Room: CNRC-2048
Houston, TX, 77030
United States

Education

MD from Medical College Of Pennsylvania/Drexel University
06/1973 - Philadelphia, Pennsylvania, United States
PhD from Massachusetts Institute Of Technology
02/1980 - Cambridge, Massachusetts, United States
Nutritional Biochemistry and Metabolism
Clinical Fellowship at Boston Children's Hospital/Harvard Medical School
06/1980 - Boston, Massachusetts, United States
Pediatric Gastroenterology, Hepatology and Nutrition
Clinical Fellowship at Massachusetts General Hospital/Harvard Medical School
02/1980 - Boston, Massachusetts, United States
Pediatric Clinical Research
Clinical Fellowship at Shriners Burns Institute
02/1980 - Boston, Massachusetts, United States
Pediatric Clinical Research
Residency at Montreal Children's Hospital/McGill University
06/1976 - Montreal, Quebec, Canada
Pediatrics
BA from Seton Hill University
05/1969 - Greensburg, Pennsylvania, United States
Biology

Certifications

Texas Medical Board
American Board of Pediatrics
American Board of Pediatric Gastroenterology

Honors & Awards

Distinguished Service Award Nominee
Given in recognition of excellence and service to the field of pediatric gastroenterology, hepatology, and nutrition by achieving national and/or international recognition in their field.
North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition (01/2013)
Pediatric Advisory Committee Service Award
Given in appreciation for scientific contributions and service to The Pediatric Advisory Committee.
Food and Drug Administration (01/2012)
Health Care Heroes Award Finalist
Given in recognition for philanthropy service.
Houston Business Journal sponsors (01/2009)
Mayor’s Volunteer Houston Award
Given in recognition for outstanding volunteer service in Houston.
City of Houston Mayor's Office (01/2006)
Humanism in Medicine Award
Given in recognition of an individual who embodied the finest qualities in a teacher of healing.
Association of American Medical Colleges (01/2004)
Giving with a Heart Award
Given in recognition for community volunteerism.
Women of Color Quilters, United States Department of Agriculture/Agricultural Research Service Children’s Nutrition Research Center, Houston, TX (01/2004)
Award of Excellence for Best Practice to ÌÇÐÄÊÓÆµ of Medicine
Given in recognition for participation in the development of BRAIN (Biomedical Research and Assurance Information Network), sponsored by the Office for Human Research Protections, Department of Health and Human Services, Washington, DC.
Health Improvement Institute, Bethesda, MD (01/2002)
Texas Dietetic Association Bluebonnet Award
Given in recognition of an individual who is not a dietitian but who has contributed significantly to the advancement of nutrition and dietetics in Texas.
Texas Dietetic Association (01/2002)
Houston Dietetic Association Bluebonnet Award
Given in recognition of an individual who is not a dietitian but who has contributed significantly to the advancement of nutrition and dietetics within the local medical community.
Houston Dietetic Association (01/2002)
SAVVY Award
Given in recognition of 18 years of voluntary community service and leadership to Casa de Esperanza de los Ninos, Inc., a crisis care agency for abused and neglected children and children with HIV.
Foley’s and the Houston Chronicle (01/2002 - 12/2002)

Professional Interests

  • Rett Syndrome
  • Methyl-CpG-Binding Protein 2
  • Growth Disorders
  • Lactation
  • Dietary Proteins

Professional Statement

Our research seeks to understand the impact of diet on gastrointestinal health and quality of life in children and young adults with rare genetic disorders. In Rett syndrome (RTT), a disorder caused by mutations in the MECP2 gene, 90% of affected individuals develop gastrointestinal problems that affect their health and quality of life. The mechanisms by which MECP2 alters gastrointestinal function in RTT is likely to have a dietary component.
We currently are characterizing the composition of the intestinal microbiome and metabolome in children and young adults with RTT. Our finding of higher bacterial richness and α-diversity among RTT individuals who consumed table foods rather than a milk-based formula suggests a potential benefit of a vegetable-rich, fiber-rich diet. Bacteroides was the predominant genus among all diet groups, but the genus Prevotella was common in individuals who consumed table food, and the genus Bifidobacterium was prominent in individuals who received formula as their primary food source. The lower level of dietary, fecal and plasma glutamate concentrations, the latter in association with abdominal gas bloating, raises the possibility of aberrant neurochemistry and neurologic function in these individuals.

Websites

Selected Publications

  • Baranowski T, Motil KJ. " " Nutrients. 2021 Aug ; 13 (8) : 2730.
    Pubmed PMID: .
  • Thapa S, Venkatachalam A, Khan N, Naqvi M, Balderas M, Runge JK, Haag A, Hoch KM, Glaze DG, Luna RA, Motil KJ. " " PLoS One. 2021 May ; 16 (5) : e0251231.
    Pubmed PMID: .
  • Motil KJ, Khan N, Coon JL, Schultz RJ, Barrish JO, Suter B, Pehlivan D, Schultz RJ, Glaze DG. " " J Pediatr Gastroenterol Nutr. 2021 ; 72 (3) : 354-60.
    Pubmed PMID: .
  • Fu C, Armstrong D, Marsh ED, Liebermam DN, Motil KJ, Witt R, Standridge S, Nues P, Lane J, Dinkel T, Coenraads M, von Hehn J, Jones M, Hale K, Suter B, Glaze DG, Neul JL, Percy A, Benke TA. " " BMJ Paediatr Open. 2020 ; 4 (1) : e000717.
    Pubmed PMID: .

Memberships

North American Society for Pediatric Gastroenterology, Hepatology, and Nutrition
Member (01/1982)
American Institute of Nutrition
Member (01/1991)
American Academy of Pediatrics
Member (01/1987)

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