Jed Gregory Nuchtern

Jed Gregory Nuchtern, M.D.

Professor of Surgery

(832) 822-3135

Positions

Professor of Surgery: Division of Pediatric Surgery
��Ƶ of Medicine

William J. Pokorny, M.D. Professorship in Pediatric Surgery: ��Ƶ of Medicine

Professor of Surgery: Division of Pediatric Surgery
Texas Children's Hospital

Addresses

Texas Children's Hospital (Clinic): Mark A. Wallace Tower
6701 Fannin Street
Houston, TX, 77030
United States
Phone: (832) 822-3135

Education

A.B. from Princeton University: 01/1979 - Princeton, NJ, United States

A.M. from Harvard University: 01/1981 - Cambridge, MA, United States

Advanced Training from National Institutes Of Health: 01/1988 - Bethesda, MD, United States

M.D. from Harvard Medical School: 01/1985 - Boston, MA, United States

Advanced Training from University Of Washington Hospital: 01/1990 - Seattle, WA, United States

Advanced Training from ��Ƶ Of Medicine Affiliate Hospitals: 01/1993 - Houston, TX, United States

Advanced Training from University Of Washington Hospital: 01/1985 - Seattle, WA, United States

Certifications

Board Certified - Pediatric Surgery: American Board of Surgery

Board Certified - General Surgery: American Board of Surgery

Board Certified - Surgical Critical Care: American Board of Surgery

Honors & Awards

Master Clinician Award for Excellence in Patient Care: ��Ƶ of Medicine

Top Doctor: U.S.News & World Report

Top Doctors for Kids: Houston Magazine

America’s Top Doctors for Cancer

Best Doctors in America

Distinguished Surgeon Award: Greater Houston AORN, 2011

Who’s Who in America: Marquis

2020 Top Doctor: Pediatric Surgery: Houstonia Magazine

Professional Interests

Pediatric surgical oncology
Adrenal tumors

Professional Statement

Dr. Jed G. Nuchtern is committed to providing pediatric surgical care with special attention to the surgical needs of children with cancer and the needs of their families. This philosophy combines dedication to exceptional education and training, advanced research, and the development of newer and better treatments and procedures.

Dr. Nuchtern takes an active role in the education and mentoring of the fellows, and residents and medical students on rotation to the Pediatric Surgery Service at Texas Children’s Hospital.

Dr. Nuchtern leads a collaborative research program that includes translational and clinical research on developing new treatments for pediatric solid tumors, particularly neuroblastoma. The primary focus in his laboratory is identifying new targets for neuroblastoma therapy. Bioinformatic studies have identified several proteins whose expression is increased in high-risk neuroblastoma tumors. The laboratory has validated these findings and demonstrated that blocking the expression of these target proteins decreases tumor growth and progression. Current research seeks to identify the pathways through which these molecules affect tumor progression.

In addition to these translational studies, Dr. Nuchtern is involved in clinical research on neuroblastoma in infants. Through the Children’s Oncology Group, he designed and implemented a prospective international study investigating the safety and efficacy of expectant observation as the primary treatment modality for infants with low risk adrenal tumors.

Websites

Pediatric Surgery Residency

Our first 'Mission Abroad' Returns from Tanzania

Residents' Research Recognized at International Oncology Congress

Center for Global Surgery

Selected Publications

Kitagawa RS, Satyan KB, Relyea K, Dauser RC, Nuchtern JG, Minifee PK, Whitehead WE, Curry DJ, Luerssen TG, Jea A. " " Spine. 2010 Apr 20; 35 (9) : E347-50.
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Baxter PA, Thompson PA, McGuffey LM, Gibson BW, Dauser RC, Nuchtern JG, Shi C, Inloes R, Choy G, Redkar S, Blaney SM. " " Cancer Chemother. Pharmacol.. 2011 Apr ; 67 (4) : 809-12.
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Shang X, Vasudevan SA, Yu Y, Ge N, Ludwig AD, Wesson CL, Wang K, Burlingame SM, Zhao YJ, Rao PH, Lu X, Russell HV, Okcu MF, Hicks MJ, Shohet JM, Donehower LA, Nuchtern JG, Yang J. " " Oncogene. 2010 Sep 2; 29 (35) : 4938-46.
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Baxter PA, Nuchtern JG, Guillerman RP, Mahoney DH, Teruya J, Chintagumpala M, Yee DL. " " Pediatr Blood Cancer. 2009 Mar ; 52 (3) : 392-4.
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Shang X, Burlingame SM, Okcu MF, Ge N, Russell HV, Egler RA, David RD, Vasudevan SA, Yang J, Nuchtern JG. " " Mol. Cancer Ther.. 2009 Aug ; 8 (8) : 2461-9.
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Muscal JA, Thompson PA, Giranda VL, Dayton BD, Bauch J, Horton T, McGuffey L, Nuchtern JG, Dauser RC, Gibson BW, Blaney SM, Su JM. " " Cancer Chemother. Pharmacol.. 2010 Feb ; 65 (3) : 419-25.
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Vasudevan SA, Shang X, Chang S, Ge N, Diaz-Miron JL, Russell HV, Hicks MJ, Ludwig AD, Wesson CL, Burlingame SM, Kim ES, Khan J, Yang J, Nuchtern JG. " " Mol. Cancer Ther.. 2009 Aug ; 8 (8) : 2478-89.
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Monclair T, Brodeur GM, Ambros PF, Brisse HJ, Cecchetto G, Holmes K, Kaneko M, London WB, Matthay KK, Nuchtern JG, von Schweinitz D, Simon T, Cohn SL, Pearson AD. " " J. Clin. Oncol.. 2009 Jan 10; 27 (2) : 298-303.
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Kilburn LB, Bonate PL, Blaney SM, McGuffey L, Nuchtern JG, Dauser R, Thompson P, Gibson BW, Berg SL. " " Cancer Chemother. Pharmacol.. 2009 Jul ; 64 (2) : 335-40.
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Plon SE, Pirics ML, Nuchtern J, Hicks J, Russell H, Agrawal S, Zbuk K, Eng C, Hegde M, Chin EL. " " N. Engl. J. Med.. 2008 Jul 31; 359 (5) : 537-9.
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Hirschmann-Jax C, Foster AE, Wulf GG, Nuchtern JG, Jax TW, Gobel U, Goodell MA, Brenner MK. " " Proc. Natl. Acad. Sci. U.S.A.. 2004 Sep 28; 101 (39) : 14228-33.
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Nuchtern JG, London WB, Barnewolt CE, Naranjo A, McGrady PW, Geiger JD, Diller L, Schmidt ML, Maris JM, Cohn SL, Shamberger RC. " " Ann. Surg.. 2012 Oct ; 256 (4) : 573-80.
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Hsu VW, Yuan LC, Nuchtern JG, Lippincott-Schwartz J, Hammerling GJ, Klausner RD. " " Nature. 1991 Aug 1; 352 (6334) : 441-4.
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Gwilliam NR, Lazar DA, Brandt ML, Mahoney DH, Wesson DE, Mazziotti MV, Nuchtern JG, Lee TC. " " J. Pediatr. Surg.. 2012 Aug ; 47 (8) : 1537-41.
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Nuchtern JG, Bonifacino JS, Biddison WE, Klausner RD. " " Nature. 1989 May 18; 339 (6221) : 223-6.
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Nuchtern JG, Biddison WE, Klausner RD. " " Nature. 1990 Jan 4; 343 (6253) : 74-6.
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Fallon SC, Slater BJ, Nuchtern JG, Cass DL, Kim ES, Lopez ME, Mazziotti MV. " " J. Pediatr. Surg.. 2013 May ; 48 (5) : 1044-8.
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Nuchtern JG, Harberg FJ. " " Semin. Pediatr. Surg.. 1994 Nov ; 3 (4) : 233-43.
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Russell HV, Hicks J, Okcu MF, Nuchtern JG. " " J. Pediatr. Surg.. 2004 Oct ; 39 (10) : 1506-11.
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Zhang L, Plon SE, Nuchtern JG, Burlingame S, Blaney S, Rousseau R, Berg S. " " Anticancer Drugs. 2004 Oct ; 15 (9) : 883-8.
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Honeycutt KA, Chen Z, Koster MI, Miers M, Nuchtern J, Hicks J, Roop DR, Shohet JM. " " Oncogene. 2006 Jul 6; 25 (29) : 4027-32.
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Rossig C, Bollard CM, Nuchtern JG, Rooney CM, Brenner MK. " " Blood. 2002 Mar 15; 99 (6) : 2009-16.
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Velanovich V, Ledbetter D, McGahren E, Nuchtern J, Schaller R. " " Arch Surg. 1992 Jul ; 127 (7) : 864.
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Kerr JZ, Hicks MJ, Nuchtern JG, Saldivar V, Heim-Hall J, Shah S, Kelly DR, Cain WS, Chintagumpala MM. " " Cancer. 1999 Jan 1; 85 (1) : 220-30.
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Vasudevan SA, Nuchtern JG, Shohet JM. " " World J Surg. 2005 Mar ; 29 (3) : 317-24.
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Miniati D, Gay AN, Parks KV, Naik-Mathuria BJ, Hicks J, Nuchtern JG, Cass DL, Olutoye OO. " " J. Pediatr. Surg.. 2008 Jul ; 43 (7) : 1301-7.
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Gross E, Chen MK, Lobe TE, Nuchtern JG, Rao BN. " " Pediatr. Surg. Int.. 1997 Sep ; 12 (7) : 529-31.
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Egler RA, Burlingame SM, Nuchtern JG, Russell HV. " " Clin. Cancer Res.. 2008 Nov 1; 14 (21) : 7028-34.
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Miltenburg DM, Nuchtern JG, Jaksic T, Kozinetiz C, Brandt ML. " " J. Pediatr. Surg.. 1998 Jun ; 33 (6) : 874-9.
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Sarkar AK, Nuchtern JG. " " Cancer Res.. 2000 Apr 1; 60 (7) : 1908-13.
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Sarkar AK, Burlingame SM, Zang YQ, Dulai V, Hicks MJ, Strother DR, Nuchtern JG. " " J. Immunother.. ; 24 (4) : 305-11.
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McLoughlin GS, Nuchtern JG, Dauser RC, Sciubba DM, Gokaslan ZL, Wolinsky JP. " " 2008 Jun ; 1 (6) : 474-6.
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Miltenburg DM, Nuchtern JG, Jaksic T, Kozinetz CA, Brandt ML. " " Am. J. Surg.. 1997 Dec ; 174 (6) : 741-4.
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Shohet JM, Hicks MJ, Plon SE, Burlingame SM, Stuart S, Chen SY, Brenner MK, Nuchtern JG. " " Cancer Res.. 2002 Feb 15; 62 (4) : 1123-8.
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Vasudevan SA, Skoko J, Wang K, Burlingame SM, Patel PN, Lazo JS, Nuchtern JG, Yang J. " " Biochem. Biophys. Res. Commun.. 2005 May 6; 330 (2) : 511-8.
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Nuchtern J, McGuffey L, Durfee J, Dauser R, Blaney SM. " " Comp. Med.. 2000 Oct ; 50 (5) : 486-9.
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Chavan RS, Patel KU, Roy A, Thompson PA, Chintagumpala M, Goss JA, Nuchtern JG, Finegold MJ, Parsons DW, López-Terrada DH. " " Pediatr Blood Cancer. 2012 Jun ; 58 (6) : 1006-7.
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Hassan SF, Mathur S, Magliaro TJ, Larimer EL, Ferrell LB, Vasudevan SA, Patterson DM, Louis CU, Russell HV, Nuchtern JG, Kim ES. " " J. Pediatr. Surg.. 2012 Jun ; 47 (6) : 1261-6.
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Fallon SC, Kim ES, Naik-Mathuria BJ, Nuchtern JG, Cassady CI, Rodriguez JR. " " Pediatr Radiol. 2013 Jun ; 43 (6) : 662-7.
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Vasudevan SA, Russell HV, Okcu MF, Burlingame SM, Liu ZJ, Yang J, Nuchtern JG. " " J. Pediatr. Surg.. 2007 Jan ; 42 (1) : 148-52.
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Nuchtern JG, Baxter R, Hatch EI. " " J. Pediatr. Surg.. 1995 Jun ; 30 (6) : 771-6.
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Nuchtern JG. " " Semin. Pediatr. Surg.. 2006 Feb ; 15 (1) : 41553.
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Cass DL, Brandt ML, Patel DL, Nuchtern JG, Minifee PK, Wesson DE. " " J. Pediatr. Surg.. 2000 Nov ; 35 (11) : 1531-6.
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Sheth RD, Brandt ML, Brewer ED, Nuchtern JG, Kale AS, Goldstein SL. " " Kidney Int.. 2002 Nov ; 62 (5) : 1864-9.
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Riva L, Blaney SM, Dauser R, Nuchtern JG, Durfee J, McGuffey L, Berg SL. " " Clin. Cancer Res.. 2000 Mar ; 6 (3) : 994-7.
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Berg S, Serabe B, Aleksic A, Bomgaars L, McGuffey L, Dauser R, Durfee J, Nuchtern J, Blaney S. " " Cancer Chemother. Pharmacol.. 2001 May ; 47 (5) : 385-90.
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Brenner MK, Heslop H, Krance R, Horowitz M, Strother D, Nuchtern J, Grilley B, Martingano E, Cooper K. " " Hum. Gene Ther.. 2000 Jul 1; 11 (10) : 1477-88.
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Yu Y, Ge N, Xie M, Sun W, Burlingame S, Pass AK, Nuchtern JG, Zhang D, Fu S, Schneider MD, Fan J, Yang J. " " J. Biol. Chem.. 2008 Sep 5; 283 (36) : 24497-505.
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Thompson PA, Berg SL, Aleksic A, Kerr JZ, McGuffey L, Dauser R, Nuchtern JG, Hausheer F, Blaney SM. " " Cancer Chemother. Pharmacol.. 2004 Jun ; 53 (6) : 527-32.
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Berg SL, Bonate PL, Nuchtern JG, Dauser R, McGuffey L, Bernacky B, Blaney SM. " " Clin. Cancer Res.. 2005 Aug 15; 11 (16) : 5981-3.
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Berg SL, Stone J, Xiao JJ, Chan KK, Nuchtern J, Dauser R, McGuffey L, Thompson P, Blaney SM. " " Cancer Chemother. Pharmacol.. 2004 Jul ; 54 (1) : 85-8.
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Kerr JZ, Berg SL, Dauser R, Nuchtern J, Egorin MJ, McGuffey L, Aleksic A, Blaney S. " " Cancer Chemother. Pharmacol.. 2001 May ; 47 (5) : 411-4.
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Berg SL, Brueckner C, Nuchtern JG, Dauser R, McGuffey L, Blaney SM. " " Cancer Chemother. Pharmacol.. 2007 May ; 59 (6) : 743-7.
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Stapleton SL, Reid JM, Thompson PA, Ames MM, McGovern RM, McGuffey L, Nuchtern J, Dauser R, Blaney SM. " " Cancer Chemother. Pharmacol.. 2007 Mar ; 59 (4) : 461-6.
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Berg SL, Aleksic A, McGuffey L, Dauser R, Nuchtern J, Bernacky B, Blaney SM. " " Cancer Chemother. Pharmacol.. 2004 Aug ; 54 (2) : 127-30.
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Muscal JA, Sun Y, Nuchtern JG, Dauser RC, McGuffey LH, Gibson BW, Berg SL. " " Cancer Chemother. Pharmacol.. 2012 Apr ; 69 (4) : 943-7.
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Serabe BM, Murry DJ, Dauser R, Nuchtern J, Durfee J, McGuffey L, Berg S, Blaney SM. " " Cancer Chemother. Pharmacol.. 1999 ; 43 (5) : 415-8.
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Miniati DN, Chintagumpala M, Langston C, Dishop MK, Olutoye OO, Nuchtern JG, Cass DL. " " J. Pediatr. Surg.. 2006 Jan ; 41 (1) : 66-71.
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Carpenter RO, Schaffer RL, Maeso CE, Sasan F, Nuchtern JG, Jaksic T, Harberg FJ, Wesson DE, Brandt ML. " " J. Pediatr. Surg.. 1999 Jun ; 34 (6) : 959-61.
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Rojas Y, Warneke CL, Dhamne CA, Tsao K, Nuchtern JG, Lally KP, Vasudevan SA, Hayes-Jordan AA, Cass DL, Herzog CE, Hicks MJ, Kim ES, Austin MT. " " J. Pediatr. Surg.. 2012 Dec ; 47 (12) : 2199-204.
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Glick RD, Hicks MJ, Nuchtern JG, Wesson DE, Olutoye OO, Cass DL. " " J. Pediatr. Surg.. 2004 Apr ; 39 (4) : 522-5.
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Vasudevan SA, Cumbie TA, Dishop MK, Nuchtern JG. " " J. Pediatr. Surg.. 2006 Jan ; 41 (1) : e41-4.
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Rossig C, Nuchtern JG, Brenner MK. " " Med. Pediatr. Oncol.. 2000 Dec ; 35 (6) : 692-5.
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Vasudevan SA, Patel JC, Wesson DE, Plon SE, Finegold MJ, Nuchtern JG. " " J. Pediatr. Surg.. 2006 Apr ; 41 (4) : 658-61.
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Sheth RD, Kale AS, Brewer ED, Brandt ML, Nuchtern JG, Goldstein SL. " " Am. J. Kidney Dis.. 2001 Sep ; 38 (3) : 553-9.
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Cass DL, Hawkins E, Brandt ML, Chintagumpala M, Bloss RS, Milewicz AL, Minifee PK, Wesson DE, Nuchtern JG. " " J. Pediatr. Surg.. 2001 May ; 36 (5) : 693-9.
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Edwards MJ, Kollenberg SJ, Brandt ML, Wesson DE, Nuchtern JG, Minifee PK, Cass DL. " " J. Pediatr. Surg.. 2005 May ; 40 (5) : 850-4.
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Rossig C, Bollard CM, Nuchtern JG, Merchant DA, Brenner MK. " " Int. J. Cancer. 2001 Oct 15; 94 (2) : 228-36.
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Dilley A, Wesson D, Munden M, Hicks J, Brandt M, Minifee P, Nuchtern J. " " J. Pediatr. Surg.. 2001 Feb ; 36 (2) : 303-8.
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Russell HV, Golding LA, Suell MN, Nuchtern JG, Strother DR. " " Pediatr Blood Cancer. 2005 Dec ; 45 (7) : 916-9.
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Lazar D, Naik B, Fitch ME, Nuchtern JG, Brandt ML. " " J. Pediatr. Surg.. 2008 Jul ; 43 (7) : 1408-10.
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Fallon SC, Coker MT, Hernandez JA, Pimpalwar SA, Minifee PK, Fishman DS, Nuchtern JG, Naik-Mathuria BJ. " " J. Pediatr. Surg.. 2013 May ; 48 (5) : e9-e12.
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Nuchtern JG, Engrav LH, Nakamura DY, Dutcher KA, Heimbach DM, Vedder NB. " " J Burn Care Rehabil. ; 16 (1) : 36-42.
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Wangler MF, Chavan R, Hicks MJ, Nuchtern JG, Hegde M, Plon SE, Thompson PA. " " J. Pediatr. Hematol. Oncol.. 2013 May ; 35 (4) : 323-8.
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Saidi AS, Friedman RA, el Said H, Nuchtern JG, Fenrich AL. " " Tex Heart Inst J. 1998 ; 25 (4) : 306-8.
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Memberships

American Academy of Pediatrics: Fellow

American College of Surgeons: Fellow

American Society of Clinical Oncology: Alliance for Childhood Cancer

American Pediatric Surgical Association

Association for Academic Surgery

International Society for Pediatric Surgical Oncology

Society of Critical Care Medicine

Southwestern Surgical Congress

Society of University Surgeons

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