Positions
- Henry and Emma Meyer Chair and Professor
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Obstetrics and Gynecology
Maternal Fetal Medicine
ÌÇÐÄÊÓƵ of Medicine
Houston, TX, United States
- Professor
-
Molecular and Human Genetics
ÌÇÐÄÊÓƵ of Medicine
Houston, Texas, United States
- Director of Prenatal & Reproductive Genetics
-
ÌÇÐÄÊÓƵ of Medicine Texas Children's Hospital
Houston, Texas, United States
- Director
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Clinical Translational Research Certificate of Added Qualification (CTR-CAQ) Program
Graduate School of Biomedical Sciences
ÌÇÐÄÊÓƵ of Medicine
- Faculty Member
-
Jan and Dan Duncan Neurological Research Institute
Texas Children's Hospital
Houston, Texas, United States
- Faculty Member
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Graduate Programs in Development, Disease Models & Therapeutics; Graduate Program in Genetics & Genomics; Graduate School of Biomedical Sciences
ÌÇÐÄÊÓƵ of Medicine
Addresses
- Jan & Dan Duncan Neurological (Office)
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Room: NRI-1025.14
Houston, TX, 77030
United States
Phone: (832) 824-8156
iveyver@bcm.edu
- Texas Children's Hospital Pavilion for Women (Clinic)
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6651 Main Street Suite F420
Houston, TX, 77030
United States
Phone: (832) 826-7500
obgyn@bcm.edu
Education
- Fellowship at ÌÇÐÄÊÓƵ Of Medicine
- 06/1993 - Houston, Texas, United States
- Maternal-Fetal Medicine
- MD from University of Antwerp
- 07/1986 - Antwerp, Belgium
- Residency at University Of Antwerp affiliated hospitals
- 07/1991 - Antwerp, Belgium
- Obstetrics and Gynecology
- Clinical Fellowship at ÌÇÐÄÊÓƵ Of Medicine
- 06/1996 - Houston, Texas, United States
- Genetics
Professional Interests
- Genetics and epigenetics of reproductive disorders; Aicardi syndrome; prenatal gene-environment interactions; prenatal genetics
Professional Statement
As a physician-scientist, my research includes translational and basic research on the molecular genetics and epigenetics of human developmental and reproductive disorders with the ultimate goal of improving the diagnosis and treatment for these conditions.
Integrating clinical research with experiments in cell lines and mouse models, my lab studies maternal effect gene mutations that cause a range of health issues from infertility to pregnancy loss with multi-locus imprinting abnormalities, including molar pregnancies, and offspring with an array of birth defects.
We also do genetic research towards finding the cause of Aicardi syndrome, a rare neurodevelopmental disorder in girls that affects development of eyes and brain, causing severe seizures, and intellectual and developmental disability.
My clinical role as Director of Prenatal and Reproductive Genetics gives a unique perspective on my translational research which focuses on exploring novel methods for reproductive and prenatal genetic screening and testing, and the complexities of their integration into preconception and prenatal and perinatal care. I participated in the development and early implementation of chromosomal microarray analysis (CMA) for prenatal diagnosis and in the earliest studies on exome sequencing for prenatal diagnosis. Today, I serve as a co-PI on the large multicenter PrenatalSEQ study which evaluates different aspects of whole genome sequencing for prenatal diagnosis, including detection rates, outcomes, and psychosocial impacts of obtaining a genetic diagnosis using this new test. We are also studying new approaches for non-invasive screening for fetal chromosomal and single gene disorders, including development and validation of methods for non-invasive prenatal diagnosis using circulating fetal cells, cell-free DNA and other non-invasive markers of fetal health.
As an active translational research educator, I am passionate about mentoring the research of postdoctoral researchers, clinical fellows, junior faculty and graduate students. After being co-director for more than ten years of a graduate program in translational research, I launched a new Clinical Translational Research Certificate of Added Qualification (CTR-CAQ) program that aims to integrate translational research training into the graduate school curriculum and is funded in part by a Ruth L. Kirschstein Institutional National Research Service Award (T32).
My roles as researcher, clinician and educator positively impact my leadership in the field of prenatal genetics. I served as president of the International Society for Prenatal Diagnosis (2016-2018), and I am currently an associate editor of Prenatal Diagnosis, and co-chair of the ClinGen Prenatal Gene Curation Expert Panel, focused on better understanding the gene variants impacting non-immune hydrops, other severe prenatal conditions, and stillbirth.
Integrating clinical research with experiments in cell lines and mouse models, my lab studies maternal effect gene mutations that cause a range of health issues from infertility to pregnancy loss with multi-locus imprinting abnormalities, including molar pregnancies, and offspring with an array of birth defects.
We also do genetic research towards finding the cause of Aicardi syndrome, a rare neurodevelopmental disorder in girls that affects development of eyes and brain, causing severe seizures, and intellectual and developmental disability.
My clinical role as Director of Prenatal and Reproductive Genetics gives a unique perspective on my translational research which focuses on exploring novel methods for reproductive and prenatal genetic screening and testing, and the complexities of their integration into preconception and prenatal and perinatal care. I participated in the development and early implementation of chromosomal microarray analysis (CMA) for prenatal diagnosis and in the earliest studies on exome sequencing for prenatal diagnosis. Today, I serve as a co-PI on the large multicenter PrenatalSEQ study which evaluates different aspects of whole genome sequencing for prenatal diagnosis, including detection rates, outcomes, and psychosocial impacts of obtaining a genetic diagnosis using this new test. We are also studying new approaches for non-invasive screening for fetal chromosomal and single gene disorders, including development and validation of methods for non-invasive prenatal diagnosis using circulating fetal cells, cell-free DNA and other non-invasive markers of fetal health.
As an active translational research educator, I am passionate about mentoring the research of postdoctoral researchers, clinical fellows, junior faculty and graduate students. After being co-director for more than ten years of a graduate program in translational research, I launched a new Clinical Translational Research Certificate of Added Qualification (CTR-CAQ) program that aims to integrate translational research training into the graduate school curriculum and is funded in part by a Ruth L. Kirschstein Institutional National Research Service Award (T32).
My roles as researcher, clinician and educator positively impact my leadership in the field of prenatal genetics. I served as president of the International Society for Prenatal Diagnosis (2016-2018), and I am currently an associate editor of Prenatal Diagnosis, and co-chair of the ClinGen Prenatal Gene Curation Expert Panel, focused on better understanding the gene variants impacting non-immune hydrops, other severe prenatal conditions, and stillbirth.
Websites
Selected Publications
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Anvar Z Jochum MD Chakchouk I Sharif M Demond H To AK Kraushaar DC Wan YW Mari MC Andrews S Kelsey G Van den Veyver IB. " " Clin Epigenet. 2025 Jun ; 17 : 92.
Pubmed PMID: . -
Zemet R Parobek CM Adams AD Maktabi MA Shay L Meng L Liu P Dai H Xia F Eng C Van den Veyver IB Vossaert L. " " Prenat Diagn. 2025 Jul ; 45 : 1313-1324.
Pubmed PMID: . -
Anvar Z Chakchouk I Sharif M Mahadevan S Nasiotis ET Su L Liu Z Wan YW Van den Veyver IB. " " Reprod Sci. 2023 Sep ; 30 : 2780-2793.
Pubmed PMID: . -
Crovetti B, Maktabi MA, Erfani H, Panchalee T, Wang Q, Vossaert L, Van den Veyver I. " " Prenat Diagn.. 2021 ; 42 : 1182-9.
Pubmed PMID: .
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