Dennis T. Villareal

Dennis T. Villareal, MD

Professor

Email

dennis.villareal@bcm.edu

Positions

Professor: Medicine-Endocrinology, Diabetes and Metabolism
��Ƶ of Medicine
Houston, Texas, United States

Staff Physician: Medical Care and Research Service Lines
Michael E. DeBakey VA Medical Center
Houston, Texas, United States

Core Faculty: Center for Translational Research on Inflammatory Diseases (CTRID)
Michael E. DeBakey VA Medical Center
��Ƶ of Medicine
Houston, Texas, United States

Addresses

Michael E. DeBakey VA Medical Center (Office): Bldg 110, Rm 264
2002 Holcombe Blvd
Houston, TX, 77030
United States

Education

Fellowship at St Louis University School of Medicine: 03/1994 - St Louis, Missouri, United States; Geriatric Medicine

Residency at Washington University - Barnes-Jewish Hospital: 06/1993 - St Louis, Missouri, United States; Internal Medicine

Fellowship at Washington University - Barnes-Jewish Hospital: 06/1991 - St Louis, Missouri, United States; Endocrinology, Diabetes, and Metabolism

MD from Cebu Institute of Medicine: Cebu City, Philippines

Certifications

Endocrinology, Diabetes, and Metabolism: American Board of Internal Medicine

Honors & Awards

Academic Excellence in Clinical Research: Physician Enterprise Vision Award (07/2023)

Michael E. DeBakey M.D. Excellence in Research Award: ��Ƶ of Medicine (05/2020)

Clinical Trials Advisory Panel (CTAP) to the National Institute on Aging: NIH - National Advisory Council on Aging (11/2016 - 10/2020)

Clinical Integrative Diabetes and Obesity (CIDO) Study Section: NIH - Scientific Review Panel Standing Member (01/2010 - 12/2014)

K23 Patient-Oriented Research Career Development Award: National Institute of Health (01/2001 - 12/2005)

Elected Fellow: Gerontological Society of America (2013) American College of Physicians (2001) American College of Endocrinology (1996)

John M Kinney International Award for Nutrition and Metabolism: (01/1992)

Professional Interests

Lifestyle, hormonal, and anabolic interventions to prevent or reverse sarcopenic obesity and frailty in older adults.

Professional Statement

I am a physician-scientist with specialized training in geriatrics and endocrinology. My research focuses on lifestyle interventions to reverse frailty and improve health outcomes in older adults with obesity. In my clinical and translational laboratories, I investigate hormonal, nutritional, and behavioral strategies to slow or reverse the complications of aging, including sarcopenic obesity and type 2 diabetes. I am committed to conducting research that informs clinical practice and advances optimal treatment strategies for older adults with obesity.

Websites

Endocrinology, Diabetes and Metabolism Faculty

Center for Translational Research on Inflammatory Diseases (CTRID)

Selected Publications

Gregori G, Mediwala S, Liebschner M, Kim D, Bryant MS, Klonis N, Armamento-Villareal R, Qualls C, Villareal DT. " " Lancet Healthy Longev. 2026 Sep 30;
Pubmed PMID: .
Villareal DT, Aguirre L, Gurney AB, Waters DL, Sinacore DR, Colombo E, Armamento-Villareal R, Qualls C. " " N Engl J Med. 2017 18; 376 : 1943-55.
Pubmed PMID: .
Villareal DT, Chode S, Parimi N, Sinacore DR, Hilton T, Armamento-Villareal R, Napoli N, Qualls C, Shah K. " " N Engl J Med. 2011 ; 364 : 1219-1229.
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Colleluori G, Aguirre L, Phadnis U, Fowler K, Armamento-Villareal R, Sun X, Brunetti L, Hyoung Park J, Kaipparettu BA, Purluri N, Auetumrongsawat V, Yarasheski K, Qualls C, Villareal DT. " " Cell Metab. 2019 ; 30 (2) : 261-273.
Pubmed PMID: .
Viola V, Samanta T, Nava M, Celli A, Armamento-Villareal R, Nguyen N, Colleluori G, Barnouin Y, Napoli N, Qualls C, Kaipparettu B, Villareal DT. " " J Cachexia Sarcopenia Muscle. 2025 Feb 16; 1 : e13697.
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Gonzales-Gil A, Barnouin Y, Celli A, Viola V, Villarreal M, Nava M, Sciuk A, Qualls C, Armamento-Villareal R, Villareal DT. " " J Clin Endocrinol Metab. 2024 Apr 12;
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Celli A, Barnouin Y, Jiang B, Blevins D, Colleluori G, Mediwala S, Armamento-Villareal R, Qualls C, Villareal DT. " " Diabetes Care. 2022 ; 45 (9) : 1943-1952.
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Waters DL, Aguirre L, Gurney AB, Sinacore DR, Fowler K, Gregori G, Armamento-Villareal R, Qualls C, Villareal DT. " " J Gerontol A Biol Sci Med Sci. 2022 ; 77 (1) : 131-139.
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Armamento-Villareal R, Aguirre L, Waters DL, Napoli N, Qualls C, Villareal DT. " " J Bone Miner Res. 2020 ; 35 : 430-439.
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Ho E, Qualls C, Villareal DT. " " J Nutr Health Aging. 2022 ; 26 (6) : 552-557.
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Weiss, E. P., Albert, S. G., Reeds, D. N., Kress, K. S., Ezekiel, U. R., McDaniel, J. L., Patterson, B. W., Klein, S., & Villareal, D. T. " " Diabetes Care. 2015 ;
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Villareal DT, Banks M, Sinacore DR, Siener C, Klein S.. " " Arch Int Med. 2006 ; 166 : 860-866.
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Villareal DT. Banks, M, Siener C, Sinacore DR, Klein S.. " " Obes Res. 2004 ; 12 : 913-920.
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Panda S, Maier G, and Villareal DT. " " J Gerontol A Biol Sci Med. 2023 Jun 16; 78 : 79-85.
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Batsis JA, Villareal DT. " " Nat Rev Endocrinol. 2018 Sep ; 14 (9) : 513-537.
Pubmed PMID: .
Villareal DT, Apovian CM, Kushner RF, Klein S. " " Am J Clin Nutr. 2005 Nov ; 82 (5) : 923-934.
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Funding

Does Lifestyle Intervention in Obese Older Adults Improve Bone Quality? #R01 DK109950: Grant funding from NIH - NIDDK

Lifestyle Intervention plus Metformin to Treat Frailty in Older Veterans with Obesity #101 CX002161: Grant funding from VA Merit Review

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