Ayse Leyla Mindikoglu

Ayse Leyla Mindikoglu, M.D., M.P.H.

Professor of Medicine

(832) 355-1400

Positions

Professor of Medicine: Margaret M. and Albert B. Alkek Department of Medicine
Section of Gastroenterology and Hepatology
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Addresses

Baylor Clinic (Clinic): 6620 Main Street
Suite 1450
Houston, TX, 77030
United States
SCHEDULE APPOINTMENT - (832) 355-1400

Education

Fellowship at University of Miami Leonard M. Miller School of Medicine: 06/2005 - Miami, Florida, United States; Advanced Hepatology

Fellowship at Loyola University Medical Center: 06/2004 - Maywood, Illinois, United States; Gastroenterology and Hepatology

Residency at Bronx-Lebanon Hospital Center: 06/2001 - Bronx, New York, United States; Internal Medicine

Residency at University of Istanbul, Cerrahpasa Faculty of Medicine: Istanbul, Turkey; General Surgery (1995-1998)

MD from University of Istanbul, Cerrahpasa Faculty of Medicine: 07/1995 - Istanbul, Turkey

MPH from University of Maryland Baltimore: 12/2007 - Baltimore, Maryland, United States; Master of Public Health, Epidemiology and Biostatistics Track

Certifications

Internal Medicine: American Board of Internal Medicine

Gastroenterology: American Board of Internal Medicine

Transplant Hepatology: American Board of Internal Medicine

Honors & Awards

2023 US National Academy of Medicine Healthy Longevity Global Competition Catalyst Award for the project entitled, "Dawn-to-Dusk Dry Fasting for Rapid Reversal of Aging"

2023 Norton Rose Fulbright Faculty Excellence Award in Teaching and Evaluation

2023 Star Faculty Award for Excellence in Patient Care

2022 Women of Excellence Award

2021 Roderick D. MacDonald Research Award/Baylor St. Luke’s Medical Center

2020 Roderick D. MacDonald Research Award/Baylor St. Luke’s Medical Center

2019 Roderick D. MacDonald Research Award/Baylor St. Luke’s Medical Center

2017 Roderick D. MacDonald Research Award/Baylor St. Luke’s Medical Center

2019 Fellow, American Association for the Study of Liver Diseases: In 2019, Dr. Mindikoglu was awarded The Fellow of the American Association for the Study of Liver Diseases (FAASLD) that epitomizes excellence and contributions to AASLD and to the field of liver disease.

2017 Faculty Research Award, ��Ƶ of Medicine, Michael E. DeBakey Department of Surgery (Dr. Mindikoglu declined this award due to an another successful overlapping award)

2017 Poster of Distinction at Digestive Disease Week®, Chicago, IL

2011 Presidential Poster of Distinction at the Liver Meeting 2011 of the American Association of the Study for Liver Diseases (AASLD), San Francisco, CA

2010 Mentored Patient-Oriented Research Career Development Award (National Institutes of Health/National Institute of Diabetes and Digestive and Kidney Diseases K23)

2004 American Association for the Study of Liver Diseases Advanced Hepatology Fellowship Award

2002 Travel Grant for the 8th Methodologies in ��Ƶ Outcomes in Gastroenterology Workshop Symposium sponsored by Gastroenterology Research Group (GRG) and the American Gastroenterological Association (AGA)

2002 Third Place Abstract Presentation in Annual Research Prize Competition of the Chicago Society for Gastroenterology

2002 Winner of the Biannual Chicago Academic Debate entitled “Liver Disease: Controversies in the New Millennium”

Professional Interests

Cirrhosis and complications (Ascites, esophageal/gastric varices, gastric antral vascular ectasia, portal hypertensive gastropathy, encephalopathy, hepatocellular carcinoma, hepatorenal syndrome, portopulmonary syndrome, hepatopulmonary syndrome)
Chronic liver diseases (e.g. Fatty liver, hepatitis B, hepatitis C, autoimmune hepatitis, alcoholic hepatitis, primary biliary cholangitis, primary sclerosing cholangitis, Wilson disease, hemochromatosis, drug-induced liver injury)
Acute liver failure
Benign and malignant liver tumors
Liver transplantation (Evaluation for liver transplantation and simultaneous liver- kidney, liver-heart, liver-lung and liver-multiorgan transplantation)
Post-liver transplant management (Acute and chronic liver graft rejection, immunosuppressive medication management, treatment of post-liver transplant recurrent hepatitis and liver disease)
Endoscopy (Esophagogastroduodenoscopy, variceal banding, colonoscopy)
Intermittent fasting
Fatty liver disease

Professional Statement

Dr. Ayse Leyla Mindikoglu is board-certified in Internal Medicine, Gastroenterology, and Transplant Hepatology with more than 18 years of experience in academic clinical practice. She is a clinician, researcher, and educator.
Dr. Mindikoglu's current research studies investigate the effect of dawn-to-dusk dry fasting on human metabolism, proteome and aging.
Dr. Mindikoglu's previous research studies were focused on renal dysfunction and acute kidney injury in cirrhosis and the development of new biomarkers of glomerular filtration rate in cirrhosis. Supported by the NIH/NIDDK K23 award between 2010 and 2015 and Roderick D. MacDonald Research Award/Baylor St. Luke's Medical Center between 2017, Dr. Mindikoglu conducted several clinical studies to understand critical concepts of altered renal hemodynamics in cirrhosis and develop metabolomic biomarkers of cirrhosis.

Websites

BCM Press Release about Dr. Mindikoglu's research study

Dawn-to-sunset fasting could help those suffering from metabolic syndrome

BCM Press Release about Dr. Mindikoglu's research study

Dawn-to-sunset fasting associated with anti-cancer proteins

How fasting may prevent obesity-related insulin resistance - Medical News Today

Dawn-to-sunset fasting suggests potential new treatment for obesity-related conditions

Dawn-to-sunset fasting suggests potential new treatment for obesity-related conditions Study of 30-day Ramadan fast shows promising implications for timing and duration between meals

Abdominal Transplant & Liver Disease Clinic

Division of Abdominal Transplantation

Selected Publications

Mindikoglu AL, Park J, Opekun AR, Abdulsada MM, Wilhelm ZR, Jalal PK, Devaraj S, Jung SY. " " 2022 ; 16
Bhatti SI, Mindikoglu AL.. " " Metabol Open. 2021 ;
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Mindikoglu AL, Abdulsada MM, Jain A, Jalal PK, Devaraj S, Wilhelm ZR, Opekun AR, Jung SY.. " " Sci Rep. 2020 ;
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Mindikoglu AL, Abdulsada MM, Jain A, et al.. " " J Proteomics. 2020 ;
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Al Lami Z, Kurtca M, Atique MU, Opekun AR, Siam MS, Jalal PK, Najafi B, Devaraj S, Mindikoglu AL. " " Metabol Open. 2024 Mar ; 21
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Mindikoglu AL, Opekun AR, Sood G, Devaraj S. " " Gastroenterol Res Pract. 2017 ;
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Mindikoglu AL, Opekun AR, Putluri N, Devaraj S, Sheikh-Hamad D, Vierling JM, Goss J, Rana A, Sood G, Jalal P, Inker LA, Mohney RP, Tighiouart H, Christenson RH, Dowling TC, Weir MR, Seliger SL, Hutson WR, Howell C, Raufman JP, Magder LS, Coarfa C. " " Transl Res. ;
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Mindikoglu AL, Pappas SC. " " Clin Gastroenterol Hepatol. ;
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Mindikoglu AL, Opekun AR, Mitch WE, Magder LS, Christenson RH, Dowling TC, Weir MR, Seliger SL, Howell CD, Raufman JP, Rana A, Goss JA, Khaderi SA, Vierling JM.. " " Dig Dis Sci. 2018 ; 63 : 665-75.
Mindikoglu AL, Dowling TC, Magder LS, Christenson RH, Weir MR, Seliger SL, Hutson WR, Howell CD. " " Clin Gastroenterol Hepatol. 2016 ; 14 : 624-32.
Mindikoglu AL, Regev A, Seliger SL, Magder LS. " " Liver Transplant. 2010 ; 16 : 1147-57.
Mindikoglu AL, Dowling TC, Wong-You-Cheong JJ, Christenson RH, Magder LS, Hutson WR, Seliger SL, Weir MR. " " Am J Nephrol. 2014 ; 39 : 543-552.
Mindikoglu AL, Dowling TC, Weir MR, Seliger SL, Christenson RH, Magder LS. " " Hepatology. 2014 ; 59 : 1532-42.
Mindikoglu AL, Dowling TC, Schaub DJ, Hutson WR, Potosky DR, Christenson RH, Barth RN, LaMattina JC, Hanish SI, Weir MR, Raufman JP. " " Dig Dis Sci. 2016 ; 60 : 3491-4.
Mindikoglu AL, Magder LS, Regev A. Outcome of liver transplantation for drug-induced acute liver failure in the United States. Analysis of the United Network for Organ Sharing Database. " " Liver Transplant. 2009 ; 15 : 719-29.
Magder LS, Regev A, Mindikoglu AL. " " Transpl Int. 2012 ; 25 : 409-15.
Urrunaga N, Magder LS, Weir MR, Rockey DC, Mindikoglu AL. " " Dig Dis Sci. 2016 ; 61 : 309-16.
Mindikoglu AL, King D, Magder LS, Ozolek JA, Mazariegos GV, Shneider BL. " " J Pediatr. 2011 ; 158 : 802-7.
Mindikoglu AL, Raufman JP, Seliger SL, Howell CD, Magder LS. " " Transplant Proc. 2011 ; 43 : 2669-77.

Memberships

The American Association for the Study of Liver Diseases (AASLD): Fellow

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